Tag: cryo-EM

Cryo-electron microscopy structures of the zebra finch R2 retrotransposon, alone and bound to Cas9, reveal how target-primed reverse transcription initiates ...

Cryo-EM structures of human VIAAT reveal how the transporter recognizes both GABA and glycine and how chloride and proton binding ...

A comprehensive review details how deep neural networks are automating every stage of cryo-electron microscopy, from particle picking to high-resolution ...

A new Vitrobot-based protocol produces graphene oxide cryo-EM grids with 55 percent average coverage and supports apoferritin and β-galactosidase reconstructions ...

A new cryo-EM structure shows how the phage lysis protein SglPP7 locks the essential transporter MurJ in an outward-facing state, ...

Cryo-electron microscopy reveals the bacterial enzyme SacC, which builds the five-ring core shared by the anticancer drug trabectedin, stabilized by ...

A new study shows that cargo peptides physically bridge neighboring AP-1 adaptor complexes through a µ1–σ1 interface, revealing that cargo ...

Enhanced sampling molecular dynamics simulations are revealing the hidden intermediate states, allosteric networks, and kinetic pathways that static structures cannot ...

Researchers at the University of Liège and Rockefeller University have captured near-atomic-resolution cryo-EM structures of the trans-spliceosome, the essential RNA-processing ...

Hedgehog merbecoviruses use aminopeptidase N as a functional entry receptor through a structurally distinct APN-binding mode, revealing convergent evolution and ...