AI Agent Learns Expert Rules for Chromatin Data Analysis
A new Genome Biology study introduces ChromSkills, a curated library of expert-encoded Skills that makes AI agents consistent, stable and ...
Tag: chromatin
Histone Chaperone NAP1L1 Keeps Gene Expression Steady in Stem Cells
A systematic screen combining single-cell RNA sequencing with ChIP-seq data has identified the histone chaperone NAP1L1 as a stabilizer of ...
Hibernating Hamsters Rewrite Their Histones, Not Their DNA, to Survive Winter
A new study of Syrian hamster liver shows that facultative hibernation is accompanied by dynamic changes in histone lysine acetylation ...
Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity
New research in Nature shows that the histone readers MLLT1 and MLLT3 license the antibody-mutating enzyme AID at specific genomic ...
Epigenetic Switch Revealed: How DNA Methylation Shapes a Seedling’s Response to Light
New research shows that losing non-CG DNA methylation makes Arabidopsis seedlings hypersensitive to light, revealing an epigenetic layer that tunes ...
Lost DNA Fragment Weakens the Inheritance of Methylation Patterns in Plants
Two independent studies converge on a 2.7 kilobase DNA deletion that reduces the fidelity of methylation inheritance in plants, suggesting ...
Epigenetic Editing Steps Closer to the Clinic as Bioengineering Tools Mature
The EpiBio-24 conference in Amsterdam showcased maturing epigenetic engineering tools, durable gene silencing in animal models, and growing clinical momentum ...
Open Chromatin Is Not So Open: Active Genes Ride on Condensed Domains
New simulations reveal that euchromatin is mostly condensed into dense domains, with short active regulatory regions protruding on their surfaces ...
Gravity leaves the human genome largely unfazed, microgravity simulator reveals
NYU physicists built a custom microgravity simulator and found that the human genome's organization and dynamics remain robust after 24 ...
Epigenetics Moves From Lab Bench to Bedside as Naples Conference Showcases Bold Advances
The 4th Clinical Epigenetics International Conference in Naples highlighted rapid progress in epigenetic mechanisms, editing technologies, and therapies for cancer, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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