Fungal enzyme RTT109 proves essential for inheriting silenced chromatin
A new study in Neurospora crassa shows that the replication-linked histone acetyltransferase RTT109, acting independently of its known product H3K56 ...
Tag: chromatin
Why Some Neurons Survive: Identity Maintenance May Set the Threshold of Neurodegeneration
A new PLOS Biology essay proposes that a neuron's capacity to maintain its subtype-defining gene-regulatory machinery may set the stress ...
Fungal Genome Hotspots Supercharge Production of Plant-Derived Drug Physcion
Scientists harnessed piggyBac transposon mapping and Hi-C chromatin analysis in Penicillium rubens to identify expression hotspots that boosted production of ...
RBBP5 Emerges as a Master Epigenetic Switch Controlling the Cell’s 12-Hour Proteostasis Clock
A new PLOS Biology study identifies the COMPASS complex subunit RBBP5 as the central epigenetic regulator of the cell's 12-hour ...
When Chromatin Wobbles, Cells Pay a Metabolic Price, Study Finds
A PLOS Genetics study shows that destabilizing chromatin through a histone H3 mutation hyperactivates the nutrient-sensing TORC1 pathway and triggers ...
Computational Microscope Opens a New Window on Chromatin Folding
An international team has developed OpenCGChromatin, an open-source simulation tool that acts as a computational microscope to reveal how chromatin ...
A Molecular License to Change: How One Gene Unlocks Natural Cell Identity Switching
New research in C. elegans reveals that the gene lin-15A enables natural cell identity conversion by weakening chromatin-based safeguards rather ...
Tiny Alga’s Oddball Chromosomes Live in Their Own Private Nuclear Neighborhoods
The first Hi-C analysis of the tiny alga Ostreococcus tauri shows that its enigmatic low-GC outlier chromosomes fold into sharply ...
Two Master Genes That Decide Whether Blood Cells Are Born or Turn Cancerous
A new review details how the Runx1 and Gata2 transcription factors architect the epigenetic landscape of blood formation and how ...
Epigenetics Beyond the Clinic: A New Journal Charts the Field’s Next Frontier
The launch of the open access journal Epigenetics Communications marks a push to understand dynamic epigenetic networks, publish negative results ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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