How Metagenomics and Metabolomics Are Joining Forces to Find New Antibiotics
A new review in Frontiers in Chemical Biology outlines how combining metagenomics and metabolomics can link microbial genomes to bioactive ...
Tag: chemical biology
From Stroke Recovery to Superbug Killers: Chemical Biology’s New Toolkit
A new Frontiers in Chemistry research collection showcases seven studies spanning stroke neuroprotection, anticancer gold complexes, covalent inhibitors, lipidated peptides, ...
Light-Activated Molecular Degraders Put Protein Destruction Under Remote Control
Chemists have developed ruthenium-based photocaged PROTACs, called RuPHOTACs, that can be switched on with low-energy red light to selectively degrade ...
Cancer Drug in Clinical Trials May Work Through an Entirely Different Target Than Assumed
A new study finds the experimental cancer drug zavondemstat and the research compound QC6352 act mainly by blocking the enzyme ...
Cell Painting Meets Thermal Proteome Profiling to Decode How Drugs Work
Researchers have combined Cell Painting imaging with thermal proteome profiling through protein-protein interaction networks to accurately identify drug targets and ...
Splicing factor SRSF1 tunes nucleolar cap pH to rescue ribosome factories after stress
A new Nature Chemical Biology study shows that the splicing factor SRSF1 is recruited to dark nucleolar caps under stress, ...
D-Amino-Acid-Powered Enzyme Cascade Maps Biomolecules Across Living Animals
Researchers have developed PRADA, an engineered enzyme cascade that uses D-amino acids to generate hydrogen peroxide locally, enabling low-toxicity protein ...
University of Kansas Lands $5.8 Million NIH Grant to Fight Antibiotic Resistance
The University of Kansas has received a $5.8 million NIH Phase 3 COBRE award to sustain its Chemical Biology of ...
From Molecular Glues to AI: The Technologies Reshaping Drug Discovery
A 58-article special issue of Molecular Diversity shows how synthetic chemistry, protein degraders, natural products, and AI-driven screening are converging ...
Evolved Lantern Tool Lights Up RNA and Protein Neighbors in Living Cells
Researchers have used directed evolution to engineer Lantern into a faster enzyme capable of labeling both RNA and protein neighbors ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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