Cell Painting Meets Thermal Proteome Profiling to Decode How Drugs Work
Researchers have combined Cell Painting imaging with thermal proteome profiling through protein-protein interaction networks to accurately identify drug targets and ...
Researchers have combined Cell Painting imaging with thermal proteome profiling through protein-protein interaction networks to accurately identify drug targets and ...
A new Nature Chemical Biology study shows that the splicing factor SRSF1 is recruited to dark nucleolar caps under stress, ...
Researchers have developed PRADA, an engineered enzyme cascade that uses D-amino acids to generate hydrogen peroxide locally, enabling low-toxicity protein ...
The University of Kansas has received a $5.8 million NIH Phase 3 COBRE award to sustain its Chemical Biology of ...
A 58-article special issue of Molecular Diversity shows how synthetic chemistry, protein degraders, natural products, and AI-driven screening are converging ...
Researchers have used directed evolution to engineer Lantern into a faster enzyme capable of labeling both RNA and protein neighbors ...
New research shows that macrophages can transfer functionally active proteins from engulfed live cells onto their own surface rather than ...
Scientists have engineered a versatile bacterial nanopore that, paired with machine learning, simultaneously identifies four major classes of biomolecules with ...
Chemists have developed a single-enantiomer covalent inhibitor that locks the cell-death protein BAX in its inactive state and protects tissue ...
Researchers at Peking University have developed a palladium-triggered bioorthogonal decaging strategy that uses iodine to reversibly silence and restore phenylalanine ...
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© 2025 Scienmag - Science Magazine