GFPT1 silencing curbs aggressive esophageal cancer cell behavior through ER stress
Cell experiments found that silencing GFPT1 reduced proliferation, migration and invasion in esophageal cancer cells, with a rescue experiment supporting ...
Tag: cell proliferation
Systematic review of 14 in vitro studies links natural products to apoptosis in salivary gland mucoepidermoid carcinoma
A systematic review of 14 in vitro studies found that natural products showed antiproliferative and proapoptotic activity in human mucoepidermoid ...
SERPINB5 promotes pancreatic adenocarcinoma progression through FBXO32-mediated regulation of epithelial-mesenchymal transition
Transcriptomic and pancreatic adenocarcinoma cell-model analyses linked SERPINB5 to malignant cell phenotypes through FBXO32-associated regulation of epithelial–mesenchymal transition.
MiR-323b-5p regulates the development of childhood asthma by targeting the RNF24 gene
A study of 76 children with asthma and 73 controls found elevated miR-323b-5p and reduced RNF24, with cell experiments supporting ...
How Polyploid Liver Cells Help the Cirrhotic Rat Liver Regenerate
A comparative study of rats and humans quantifies how somatic polyploidy, proliferation and hypertrophy each contribute to liver regeneration during ...
Cancer Cells Burn Energy on Futile Transcription by Shifting Their Genetic Start Lines
New research shows that cancer cells universally deregulate transcription start site selection, wasting energy on futile upstream transcription while protecting ...
Enzyme Autotaxin Drives Scarring in the Optic Nerve’s Load-Bearing Scaffold in Glaucoma
Researchers in Dublin report that the enzyme autotaxin and its lipid product lysophosphatidic acid drive fibrosis in lamina cribrosa cells ...
Estrogen Receptor Gene ESR1 Emerges as a Master Switch for Buffalo Milk Production
New research shows that the estrogen receptor gene ESR1 promotes milk fat and protein synthesis, cell proliferation, and survival in ...
Liver Cancer’s Hidden Brake: How A20 Marks a Key Tumor Protein for Destruction
New research reveals that the ubiquitin-editing enzyme A20 promotes the degradation of the pro-tumor protein osteopontin in hepatocellular carcinoma, offering ...
Lychee Seed Extract Shows Promise for Healing Oral Wounds in Lab Study
A crude extract from discarded lychee seeds proved non-toxic to human gum fibroblasts at low doses and boosted cell proliferation ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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