Tag: CD8+ T cells

A UC Davis clinical trial found that doxorubicin lymphodepletion before inhaled interleukin-15 therapy did not improve response rates in dogs ...

A combined transcriptomic and histological study of kidney biopsy tissue reveals widespread immune activation, checkpoint upregulation, and altered T-cell dynamics ...

A retrospective study of 354 patients found clonal T-large granular lymphocyte expansions in 17.2 percent of JAK2-mutated myeloproliferative neoplasm cases, ...

Single-cell sequencing of blood samples taken before and after liver transplantation reveals immune signatures that predict which patients will suffer ...

New research shows that the RNA methyltransferase METTL16 drives colorectal cancer growth and immune evasion by stabilizing BCAT1 mRNA and ...

A new study shows that exosomes released by tumor-associated macrophages carry PD-L1 that reprograms the metabolism of CD8-positive T cells, ...

Researchers found that liver cancer patients who responded poorly to conversion therapy harbored distinct bacterial communities inside their tumors, including ...

Researchers have identified a human-specific FXR-TRIM22-STAT1 checkpoint that suppresses radiation-induced antitumor immunity, and shown that the clinically approved bile acid ...

New research shows that the damage malaria sporozoites inflict while punching through host cells, sensed via a wounding response requiring ...

Blocking the collagen receptor integrin alpha-2 (CD49b) on breast cancer cells remodels the tumor immune microenvironment and synergizes with anti-PD-L1 ...