Blood Levels of Liver Cancer Drug Lenvatinib Predict Who Responds to Treatment
A multi-omics study of 194 liver cancer patients shows that lenvatinib blood concentrations above 26.5 ng/mL predict treatment response, while ...
Tag: CD8+ T cells
Common Antidepressants May Boost Immunotherapy Survival in Cancer Patients, Major Study Finds
A large target trial emulation found that cancer patients on SSRIs while receiving immune checkpoint inhibitors had significantly lower two-year ...
Fasting Starves Tumors of Taurine, Triggering Immune Cell Death in Colorectal Cancer
A new study shows intermittent fasting depletes taurine, destabilizes the PERK stress pathway in colorectal cancer cells, and triggers immunogenic ...
Orphan Nuclear Receptor Ligands Trigger Ferroptosis and Reshape Immunity in Colon Cancer
New research shows that synthetic ligands for the orphan nuclear receptors NR4A1 and NR4A2 induce iron-dependent cell death in colon ...
Malaria Parasites Must Burrow Through Cells to Spark Vaccine Protection, Study Finds
New research shows that the ability of malaria sporozoites to migrate through host cells before liver infection is a dominant ...
Viral Mimicry Revealed: SARS-CoV-2 T Cells Also Recognize Tumor Antigens
Single-cell TCR sequencing shows that SARS-CoV-2-specific CD8 T cells recognize a tumor-associated antigen through molecular mimicry, supporting viral-mimic cancer vaccines.
Common Sweetener Sucralose Shows Surprising Ability to Calm Autoimmune Attacks in Vitiligo
New research shows the artificial sweetener sucralose slows autoimmune depigmentation in mice and suppresses human CD8+ T cell activity by ...
Cancer Cell Camouflage: MnO2 Nanosheets Cloaked in Tumor Membranes Supercharge Radio-Immunotherapy
Researchers have built a cancer-cell-membrane-coated manganese dioxide nanosheet that delivers the immune adjuvant R848 directly to tumors, relieving hypoxia and ...
Exercise During Chemotherapy Reshapes Immune Cells in Breast Cancer Patients, Pilot Study Finds
A supervised twelve-week exercise programme during chemotherapy for early-stage breast cancer was feasible and safe, with exploratory evidence of cytotoxic ...
Iron-Powered Cell Death Emerges as Double-Edged Sword in Cancer’s Microenvironment
A new review in Medical Oncology maps how the tumor microenvironment can either amplify or suppress ferroptosis, the iron-dependent cell ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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