A new study links tumor-derived TNF-α, CCL4-high tumor-associated neutrophils, and suppressed T-cell activity to immunotherapy resistance in non-small cell lung ...
Preclinical research shows serine supplementation, rather than restriction, suppresses tumor growth and reinvigorates CD8+ T cells by countering tumor cell ...
In a mouse and cell study, caloric restriction and fasting enhanced radiation's tumor-killing effects through the cGAS-STING pathway while protecting ...
Single-cell and spatial profiling of pancreatic tumors reveals a reinforcing loop between mature dendritic cells and regulatory T cells, mediated ...
A preclinical study reports that ginseng-derived ginsenoside Rg3 binds Glut1 on tumor-associated macrophages, reprograms their metabolism, and enhances anti-PD-1 therapy ...
A new study reports that NAT10-mediated mRNA acetylation and USP19-mediated deubiquitination jointly stabilize CDH3, promoting colorectal cancer progression and immune ...
A preclinical mouse study reports that the fungal-derived compound DM28 induces SLC3A2-linked ferroptosis and increases activated T cell infiltration when ...
Engineered renal cancer assembloids reveal a tumour–fibroblast–T cell signalling axis that governs stem-like CD8+ T cell maintenance and heterogeneous responses ...
A mouse study finds that isoleucine and valine, rather than leucine, sustain c-Myc expression and proliferation in activated CD8 T ...
A new study reports that the RNA m5C methyltransferase NSUN2 suppresses CCL5-driven CD8+ T cell recruitment in lung adenocarcinoma through ...
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