Tag: cancer immunotherapy

A phase II trial found that adjuvant sintilimab monotherapy after surgery met its primary efficacy endpoint with 87.5 percent one-year ...

A new single-cell study identifies the transcription factor RBPJ and CD103-positive tissue-resident memory T cells as central drivers of successful ...

A new Nature study shows that tumor-recruited osteoclasts secrete angiopoietin-2 to destroy meningeal lymphatic vessels in dural metastasis, and that ...

New research reveals that radiotherapy induces PD-1 expression on tumor-associated monocytes through an adenosine-driven signaling pathway, creating an immunosuppressive cell ...

A new multi-disciplinary expert consensus provides a detailed framework for diagnosing and treating the skin toxicities caused by immune checkpoint ...

Xiamen University researchers report that inhibiting RNASET2, a magnesium-sensitive enzyme that clears mitochondrial double-stranded RNA, ignites innate immune signaling in ...

New research shows that radiation can make liver cancer cells more visible to natural killer cells, boosting the effectiveness of ...

A new review details how tumor-infiltrating lymphocyte, CAR-T, and TCR-engineered cell therapies are transforming melanoma treatment and the engineering breakthroughs ...

A large UK pan-cancer study finds no consistent link between the season of checkpoint inhibitor initiation and overall survival, despite ...

New research shows that immune checkpoint receptors on human gamma delta T cells are regulated in a lineage- and context-dependent ...