Two Immune Cell Armies in One Infusion: Combination NK and T Cell Therapy Shows Promise in Hard-to-Treat Tumors
A phase 1 trial found that an autologous combination of natural killer cells and tumor-primed T lymphocytes was safe and ...
Tag: cancer immunotherapy
Cancer Protein TIPE Hijacks Immune Cells to Fuel Colorectal Tumor Growth
New research reveals how the tumor protein TIPE drives colorectal cancer progression by converting macrophages into tumor-supporting M2 cells through ...
The Don’t Eat Me Signal: How CD47 Shapes Cell Clearance in Cancer, Heart Disease and the Brain
A new review details how the CD47 don't eat me signal regulates efferocytosis and shapes disease outcomes in cancer, atherosclerosis ...
Scientists Turn Complement Footprints Into a Second Strike Against Drug-Resistant Cancer Cells
Researchers engineered an anti-C4d antibody that targets complement fragments left on tumor cells that survived antibody therapy, boosting complement-mediated killing ...
Virus-Like Particles Emerge as a Unifying Platform for Vaccines, Gene Delivery, and Precision Medicine
A new review in Advanced Composites and Hybrid Materials presents virus-like particles as adaptable biohybrid nanomaterials uniting established vaccines with ...
Gut Microbes Prime Regulatory B Cells That Shape Cancer Immunotherapy Outcomes
A new review explains how gut microbes program immunosuppressive regulatory B cells through cytokine and metabolite signals, with major implications ...
Enhancers That Free Stalled Polymerase Drive Tumor-Feeding Macrophages Across Cancers
A pan-cancer single-cell epigenetic study reveals that tumor-supportive macrophages arise through distinct enhancer-driven trajectories in which releasing paused RNA polymerase ...
Organoid Platform Uncovers mITGB2 as a Promising CD4-Targeting Neoantigen in Liver Cancer
Using patient-derived hepatocellular carcinoma organoids, researchers identified mITGB2, a splice-variant-derived peptide presented by MHC class II, as a functionally immunogenic ...
Cancer Vaccines Enter a New Era as Personalized Immunotherapy Gains Momentum
A new review charts how mRNA, peptide, cell, and virus-based therapeutic vaccines, supercharged by AI-driven neoantigen prediction and combination immunotherapy, ...
Rare IL-15-Driven NK Cell Subset Supercharges T Cell Attack on Melanoma
Researchers have identified a bone marrow-derived CD11c-positive B220-positive NK cell subset selectively expanded by IL-15 that outperforms conventional NK cells ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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