Network Analysis Pinpoints Five Hub Genes Steering Hodgkin Lymphoma Pathways
An integrative bioinformatics study of 3,180 Hodgkin Lymphoma-associated genes identified TP53, STAT3, AKT1, EGFR and IL6 as the most highly ...
Tag: bioinformatics
Long non-coding RNA TMPO-AS1 flags poor outcomes in lung adenocarcinoma
A multi-database bioinformatics study identifies the long non-coding RNA TMPO-AS1 as overexpressed in lung adenocarcinoma and linked to poor survival ...
GPT-Neo Transformer Boosts Bacterial Promoter Prediction
A hybrid GPT-Neo transformer and Random Forest approach achieved 97 percent accuracy in detecting promoters in Agrobacterium tumefaciens.
New Tool Turns KEGG Reaction Class Data into Explicit Atom-to-Atom Maps
Researchers developed laveau, an algorithm that converts KEGG RCLASS annotations into double-pushout graph transformation rules and atom-to-atom maps for thousands ...
New Bayesian Model Extracts Shared Microbial Signals Across Heterogeneous Studies
Researchers have introduced a statistical model designed to predict disease from microbiome data pooled across many studies, addressing a persistent ...
New tool prunes misleading redundant pathways from gene enrichment results
PathwayDenester re-evaluates enriched pathways by testing whether their significance depends on overlapping, more significant terms, filtering out 40 to 90 ...
Single-cell study links an eight-gene program to LSC17-high acute myeloid leukemia
An integrative single-cell and bulk transcriptomic analysis identified an eight-gene non-LSC17 companion program associated with LSC17-high acute myeloid leukemia and ...
Single-Cell Map Links Endothelial Cell Genes to Lung Cancer Survival
A six-gene endothelial cell signature built from single-cell RNA sequencing data predicts survival outcomes and reveals distinct tumor microenvironment communication ...
Macrophage-linked biomarkers flagged for esophageal cancer chemoradiotherapy response in computational study
A computational study identified KRT14 and MMP10 as macrophage-associated candidate biomarkers of chemoradiotherapy response in esophageal squamous cell carcinoma.
DNA Repair Protein RPA Emerges as Poor-Prognosis Marker in Liver Cancer
A computational pan-cancer analysis links overexpression of the RPA gene family to worse survival and an immunosuppressive tumor microenvironment in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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