Tumor Suppressor ENDOD1 Slows Colorectal Cancer Growth in Cell and Mouse Studies
Laboratory and mouse experiments show that the underexpressed gene ENDOD1 suppresses colorectal cancer cell proliferation, migration, and invasion partly by ...
Tag: bioinformatics
Pan-Cancer Analysis Maps PTPN3’s Contrasting Roles Across Tumors
A multi-platform pan-cancer analysis finds PTPN3 shows cancer-type-dependent differences in expression, survival associations, genomic alterations, phosphorylation and stromal correlations.
Potassium Channel KCNH8 Slows Triple-Negative Breast Cancer by Blocking PI3K-AKT Signaling
A combined bioinformatics and experimental study finds that the potassium channel KCNH8 is reduced in breast tumors and restrains triple-negative ...
Computational Study Maps Resveratrol’s Potential Protein Targets in Lung Squamous Cell Carcinoma
A computational study combining database mining, network analysis and molecular docking identifies TP53, AKT1, IL6 and CCND1 as potential resveratrol ...
Hypergraph Embeddings Reveal How Metabolism Tracks Evolutionary Lineages
A large-scale comparison of 14 embedding methods shows that hyperedge-based representations of metabolic hypergraphs can cluster thousands of organisms in ...
Low CEBPD Expression Tied to Poor Breast Cancer Survival, Study Finds
Researchers report that the adipogenesis-related gene CEBPD is downregulated in breast tumors, serves as an independent prognostic indicator of survival, ...
New AI tool annotates single-cell data with far fewer labels
A new dual-view machine learning framework called scTrans-SVD achieved a mean Macro-F1 of 0.8820 across 13 public single-cell transcriptomic datasets ...
Three Oxidative Stress Genes Emerged as Key Players in Kidney Reperfusion Injury
A combined bioinformatic and experimental study identified FOS, FOSB and GDF15 as oxidative stress-related genes upregulated in renal ischemia-reperfusion injury ...
Tag arrays bring lossless indexing to large human pangenome graphs
Researchers have built the first practical tag array index that maps query patterns to all their positions across pangenome graphs ...
Computational study links PCB118 to estrogen receptor ESR1 in breast cancer
A computational network toxicology and molecular docking study predicts a theoretical interaction between the pollutant PCB118 and the estrogen receptor ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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