Hidden RNA Switches: New Tool Reveals lncRNAs That Define Tumor-Fighting T Cells
A new computational framework called SDSGI uncovers subtype-specific long non-coding RNAs in tumor-infiltrating CD8-positive T cells across multiple cancer types, ...
Tag: bioinformatics
Immune Gene Signature Linked to Severe Male Infertility Identified by Machine Learning
An integrated bioinformatics study has identified a twelve-gene immune-related signature that distinguishes non-obstructive azoospermia with strong accuracy and points to ...
New Dashboard Brings Protein Structure Into the Hunt for Disease-Causing Gene Variants
Researchers have developed ProtSAVI, an R-based dashboard that combines protein structure analysis with ACMG/AMP criteria to reclassify variants of uncertain ...
Sequencing Revolution Races to Rescue the World’s Fruits and Vegetables
A comprehensive new review argues that next-generation sequencing has transformed horticultural crop genomics, but bioinformatics capacity and functional validation, not ...
Ice-Inspired Algorithm Gets Smarter, Boosting Monkeypox Prediction Accuracy
Researchers have enhanced a rime-ice-inspired optimization algorithm with four adaptive strategies, achieving superior benchmark results and 95.52 percent accuracy in ...
Scellmate brings contamination-aware curation to thousands of single-cell microbial genomes
A new semi-supervised computational framework called Scellmate curates thousands of noisy single amplified genomes and maps mobile genetic elements to ...
GraTools brings speed and simplicity to pangenome variation graph analysis
Researchers have developed GraTools, an open-source command-line tool that simplifies and accelerates the exploration and manipulation of pangenome variation graphs, ...
Metax brings genome-wide coverage into focus for sharper microbial profiling
Researchers at the Helmholtz Centre for Infection Research have developed Metax, a computational tool that uses genome-wide read coverage to ...
Evolution of Estrogen Receptors Explains Why Species Respond Differently to Chemicals
An integrated study of estrogen receptor alpha evolution across 169 mammalian species reveals how ecological traits and structural mutations drive ...
White Shark Algorithm Shows Promise for Classifying High-Dimensional Cancer Data
Researchers adapted a swarm intelligence algorithm modeled on great white shark hunting behavior to select the most informative genes from ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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