Long non-coding RNA TMPO-AS1 flags poor outcomes in lung adenocarcinoma
A multi-database bioinformatics study identifies the long non-coding RNA TMPO-AS1 as overexpressed in lung adenocarcinoma and linked to poor survival ...
Tag: bioinformatics
GPT-Neo Transformer Boosts Bacterial Promoter Prediction
A hybrid GPT-Neo transformer and Random Forest approach achieved 97 percent accuracy in detecting promoters in Agrobacterium tumefaciens.
New Tool Turns KEGG Reaction Class Data into Explicit Atom-to-Atom Maps
Researchers developed laveau, an algorithm that converts KEGG RCLASS annotations into double-pushout graph transformation rules and atom-to-atom maps for thousands ...
New Bayesian Model Extracts Shared Microbial Signals Across Heterogeneous Studies
Researchers have introduced a statistical model designed to predict disease from microbiome data pooled across many studies, addressing a persistent ...
New tool prunes misleading redundant pathways from gene enrichment results
PathwayDenester re-evaluates enriched pathways by testing whether their significance depends on overlapping, more significant terms, filtering out 40 to 90 ...
Single-cell study links an eight-gene program to LSC17-high acute myeloid leukemia
An integrative single-cell and bulk transcriptomic analysis identified an eight-gene non-LSC17 companion program associated with LSC17-high acute myeloid leukemia and ...
Single-Cell Map Links Endothelial Cell Genes to Lung Cancer Survival
A six-gene endothelial cell signature built from single-cell RNA sequencing data predicts survival outcomes and reveals distinct tumor microenvironment communication ...
Macrophage-linked biomarkers flagged for esophageal cancer chemoradiotherapy response in computational study
A computational study identified KRT14 and MMP10 as macrophage-associated candidate biomarkers of chemoradiotherapy response in esophageal squamous cell carcinoma.
DNA Repair Protein RPA Emerges as Poor-Prognosis Marker in Liver Cancer
A computational pan-cancer analysis links overexpression of the RPA gene family to worse survival and an immunosuppressive tumor microenvironment in ...
Tumor Suppressor ENDOD1 Slows Colorectal Cancer Growth in Cell and Mouse Studies
Laboratory and mouse experiments show that the underexpressed gene ENDOD1 suppresses colorectal cancer cell proliferation, migration, and invasion partly by ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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