Multi-omics study links autophagy and ER stress to PFOA toxicity in sperm precursor cells
A multi-omics study in GC-1 spermatogonial cells links PFOA exposure to altered autophagy, ER stress signaling and oxidative imbalance, with ...
Tag: autophagy
Traditional Chinese Medicine Formula Shows Ovarian Protection in Rat Study
A rat study published in Biological Research reports that Dingkun Pill reduced oxidative stress, follicular depletion, and cell death in ...
Deleting TBK1 Entirely Slows Disease Progression in ALS Model Mice
Complete deletion of the ALS-linked gene TBK1 suppresses microglial activation and extends disease duration in SOD1-ALS model mice, a new ...
Goji Berry Polysaccharides Shield Stressed Neurons by Restoring Ribosomal Protein RPLP1
A new cell-culture study reports that goji berry polysaccharides protect mouse neurons from ischemia-reperfusion injury by restoring the ribosomal protein ...
Review frames Wnt/β-catenin as a metabolic hub linking traditional Chinese medicine to osteoporosis
A new review proposes osteoblast metabolic senescence as a key driver of osteoporosis and outlines how traditional Chinese medicine might ...
Frontiers Retracts Corrigendum on ABTL0812 in Glioblastoma Over Image Concerns
Frontiers in Oncology has retracted a 2025 corrigendum on the anticancer effects of ABTL0812 in glioblastoma models after the authors ...
mTORC1 may act as a transition switch in ME/CFS post-exertional malaise
A new review proposes mTORC1 as a transition switch linking mitochondrial dysfunction to post-exertional malaise in ME/CFS, while noting that ...
Smart Hydrogel Delivers CRISPR Gene Editing to Treat Degenerating Spinal Discs in Rats
A pH- and ROS-responsive hydrogel carrying CRISPR-Cas9 silenced the TRPV4 calcium channel in rat discs, restoring autophagic flux and slowing ...
Rapamycin impairs viability and reshapes autophagy gene expression in Schistosoma mansoni
A laboratory study finds that rapamycin reduces the viability of both juvenile and adult Schistosoma mansoni and alters autophagy gene ...
STAM protein suppresses kidney cancer through a dual EGFR and AKT mechanism
New preclinical research shows the STAM protein suppresses clear cell renal cell carcinoma by inactivating EGFR and degrading AKT, inducing ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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