Autophagy’s Double-Edged Role in Womb Scarring and Age-Related Fertility Decline
A new review in Reproductive Sciences argues that autophagy, the cell's recycling machinery, plays a context-dependent dual role in endometrial ...
Tag: autophagy
E3 Ligase TRIM37 Steers Cilia Growth by Tagging p62 and Tuning Autophagy
A new study reveals that the E3 ubiquitin ligase TRIM37 regulates primary cilium assembly by ubiquitinating the autophagy receptor p62 ...
Broken Cellular Recycling Plants Emerge as Common Thread in Neurodegenerative Disease
A new review in Nature Reviews Neurology argues that defective lysosomal function is a central, genetically validated driver of Parkinson ...
Cellular Recycling Reworked: Autophagy Follows Surprising Sex- and Cell-Type Rules in Human Aging
Direct measurements of autophagy flux in human skin cells, induced neurons, and immune cells reveal sex- and cell-type-specific remodeling during ...
Rare Muscle Diseases Tied to Blood Protein Disorders May Be One Spectrum
A new study argues that scleromyxedema-associated myopathy and the recently described VAMMGAS are related manifestations of monoclonal gammopathy of clinical ...
Kisspeptin-10 Shows Promise Against Obesity-Driven Testicular Damage in Rat Study
A new rat study shows the puberty-regulating hormone Kisspeptin-10 reduces testicular oxidative stress, improves sperm quality, and boosts mitophagy-related proteins ...
Tiny RNA Hubs May Steer Inflammation in Aging Cells
A new review argues that stress granules and their RNA-binding proteins act as context-dependent modulators of cellular senescence and inflammation ...
Hidden RNA Switches That Sculpt the Human Fetal Gut Revealed in New Timeline of Autophagy
A new genomic study maps the dynamic expression of autophagy-related circular and long noncoding RNAs across early human fetal intestinal ...
Rapamycin Nanoparticles Rejuvenate Aging Spine Discs by Silencing a Cellular Aging Switch
Rapamycin-loaded nanoliposomes inhibited mTORC1-driven senescence in rat disc cells and slowed intervertebral disc degeneration in vivo, pointing toward an injectable ...
Cellular Recycling in the Brain’s Appetite Center May Shape Obesity Risk
A new review argues that autophagy in hypothalamic POMC and AgRP neurons exerts opposing effects on appetite and energy balance, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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