Immune Cell Enzyme p38 MAPK Emerges as a Molecular Fingerprint in Rare Nerve Diseases
A new study links elevated p38 MAPK activity in immune cells to multifocal motor neuropathy severity and shows that intravenous ...
Tag: autophagy
CoQ10 Restores Aging Megakaryocyte Function Through a Newly Identified Autophagy Pathway
New research in naturally aged mice shows that dietary coenzyme Q10 rejuvenates platelet-producing megakaryocytes by restoring COPS3-dependent autophagy, taming the ...
Moderate Exercise Rewires Autophagy Genes and Eases Methamphetamine Withdrawal in Rats
A new rat study shows that moderate-intensity continuous training during methamphetamine withdrawal restores frontal cortex autophagy-related gene expression and improves ...
How Autophagy’s Dual Role Shapes Inflammatory Bowel Disease
A sweeping new review maps how canonical, selective, and non-autophagic functions of autophagy genes jointly determine the course of inflammatory ...
Autophagy Rewrites the Rules of Aging, Cell by Cell
A new human study shows that autophagy, the cell's recycling system, changes with age in cell-type- and sex-specific ways rather ...
Cells Tag Faulty Glycogen for Destruction, Study Reveals
Researchers have discovered that the E3 ubiquitin ligase RNF213 directly tags aberrant, poorly branched glycogen for autophagic degradation, revealing a ...
From Reversible to Irreversible: A New Three-Stage Model Redefines Ovarian Metabolic Disease
A new review proposes that polyendocrine metabolic ovarian syndrome progresses through three biological stages, from a reversible plasticity-dominant state to ...
TGF-β2 Rewires Colon Cancer Cells to Survive Doxorubicin Through Autophagy and HMGB1
New research shows that the TGF-β2 signaling molecule steers metastatic colon cancer cells toward autophagy-mediated resistance to the chemotherapy drug ...
How Failing Cellular Housekeeping Fuels Brain Disease Through a Viral Alarm System
A new review in the Journal of Translational Medicine details how impaired mitophagy allows mitochondrial DNA to trigger cGAS–STING-driven neuroinflammation ...
Gastric Cancer circRNA Study Retracted After Image Duplication and Contaminated Cell Line Concerns
Molecular Cancer has retracted a 2019 gastric cancer study on circNRIP1 and microRNA-149-5p after image duplication across multiple papers and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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