Tiny RNA Hubs May Steer Inflammation in Aging Cells
A new review argues that stress granules and their RNA-binding proteins act as context-dependent modulators of cellular senescence and inflammation ...
Tag: autophagy
Hidden RNA Switches That Sculpt the Human Fetal Gut Revealed in New Timeline of Autophagy
A new genomic study maps the dynamic expression of autophagy-related circular and long noncoding RNAs across early human fetal intestinal ...
Rapamycin Nanoparticles Rejuvenate Aging Spine Discs by Silencing a Cellular Aging Switch
Rapamycin-loaded nanoliposomes inhibited mTORC1-driven senescence in rat disc cells and slowed intervertebral disc degeneration in vivo, pointing toward an injectable ...
Cellular Recycling in the Brain’s Appetite Center May Shape Obesity Risk
A new review argues that autophagy in hypothalamic POMC and AgRP neurons exerts opposing effects on appetite and energy balance, ...
Ancient Chinese Herbal Formula Restores Skin Barrier in Eczema by Switching On a Key Repair Pathway
A clinical trial and a series of animal and cell experiments show that the traditional Chinese formula gu-ben-hua-shi repairs the ...
Recycling Machinery in Sertoli Cells Proves Essential for Male Fertility
A Sertoli cell-specific Beclin1 knockout study in mice reveals that autophagy in these nurse cells underpins the blood-testis barrier and ...
Shrimp Rewrite Their Genes to Thrive in Microbe-Rich Biofloc Farms
New research shows that Pacific white shrimp raised in biofloc systems reprogram more than 1,200 midgut genes involved in protein ...
Polyamine Metabolism Emerges as a Central Player in Neurological Disease
A new review links dysregulated polyamine metabolism to Alzheimer's, Parkinson's, ALS, and other neurological disorders, outlining molecular mechanisms and emerging ...
Ancient Origins of Autophagy Traced from Bacteria to Complex Eukaryotic Cells
A new review traces the evolutionary origins of autophagy from prokaryotic gene homologs to the sophisticated pathway present in the ...
Ancient Chinese Herbal Formula Shows Promise Against Disc Degeneration
A classical Chinese herbal formula, Juanbi Tang, attenuates intervertebral disc degeneration in rats by suppressing p38MAPK/NF-κB signaling, activating Atg5-dependent autophagy, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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