Study Links DJ-1 Protein to Glioblastoma Growth via UBA52 Signaling Pathway
Researchers found that the protein DJ-1 promotes glioblastoma progression through the UBA52-mediated NF-κB signaling pathway in cell and mouse models.
Tag: apoptosis
Promoter Hypermethylation Downregulates LncRNA HAND2-AS1 in Bladder Cancer Models
Promoter hypermethylation suppresses the long non-coding RNA HAND2-AS1 in bladder cancer, while experimental restoration inhibits tumor growth and activates interferon-related ...
ALDH2 Suppresses Multiple Myeloma Progression by Restraining the E2F Signaling Pathway
Researchers found that ALDH2 acts as an independent favorable prognostic biomarker in multiple myeloma, curbing cancer cell proliferation and promoting ...
DSN1 Promotes Basal-Like Breast Cancer Tumor Growth Through CDC25C Pathway Activation
Researchers found that DSN1 promotes cell proliferation and tumor growth in triple-negative and basal-like breast cancer models by activating the ...
RNA TRHDE-AS1 Suppresses Melanoma Growth by Regulating SPRED1 and MAPK Pathway
Preclinical study findings indicate that long non-coding RNA TRHDE-AS1 suppresses melanoma cell growth by upregulating SPRED1 and dampening MAPK/ERK pathway ...
Circulating MicroRNAs Track Hepatocellular Carcinoma Stages and Key Tumor Progression Biomarkers
A cross-sectional study of Egyptian patients reveals distinct stage-dependent shifts in circulating miRNA-122 and miRNA-223 linked to critical molecular pathways ...
Histone H3K9 Lactylation Promotes Liver Cancer Growth by Destabilizing SPINK13
Researchers identified an epigenetic mechanism in which histone H3K9 lactylation accelerates hepatocellular carcinoma progression by activating LUC7L2 to destabilize SPINK13 ...
LOX-1 Depletion Suppresses Cardiac Hypertrophy and Apoptosis in Rat Cardiomyopathy Models
Knockdown of LOX-1 ameliorated ethanol-induced cardiac hypertrophy and apoptosis in rodent models by restoring p38MAPK-mediated autophagy.
ZNF169 Drives Thyroid Cancer Progression by Activating Downstream Effector FBXW10
Researchers found that the nuclear protein ZNF169 promotes thyroid carcinoma progression by binding the FBXW10 promoter and driving tumor proliferation.
Circular RNA circLAMC1 suppresses non-small cell lung cancer progression in preclinical models
In preclinical models of non-small cell lung cancer, circular RNA circLAMC1 suppressed tumor progression by regulating the miR-27a-3p/PAQR3/NF-κB/p53 signaling axis.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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