Disc Degeneration Traced to a Histone Switch That Silences the Cell’s Mitochondrial Cleanup Crew
A new study shows that the chromatin protein CBX3 accelerates disc degeneration by silencing the SESN2 gene through H3K9me3 marks, ...
Tag: apoptosis
Black Wattle Tree Extract Shows Potent Anticancer Activity Against Bladder Cancer Cells
Brazilian researchers report that proanthocyanidins from black wattle bark kill bladder cancer T24 cells at low concentrations and modulate cancer-related ...
Zinc-Locked Herbal Hydrogel Attacks Tumors and Their Blood Supply at Once
Researchers have created a zinc-crosslinked rhein and pectin hydrogel that gels inside tumors, arresting melanoma cells in the G2/M phase ...
Spirulina pigment dismantles a key shield that blocks breast cancer drug response
A new cell study shows that C-phycocyanin can strip away Mcl-1-driven resistance and make the BH3-mimetic ABT-737 far more lethal ...
Hepatitis B Virus X Protein Mutation T118N Reshapes Cell Cycle and Apoptosis in Liver Cells
New research shows that the hepatitis B virus X protein T118N mutation, common in Indonesia, increases Cyclin E expression and ...
AI Reads Live Cell Videos to Predict Cancer Cell Fates Before They Happen
A Transformer deep learning model predicts cancer cell fates directly from live-cell videos with high accuracy up to eight hours ...
Silencing a Fat-Making Master Switch Pushes Pancreatic Cancer Cells Toward Self-Destruction
New research links elevated SREBF1 expression to lipid metabolism signatures in pancreatic cancer and shows that silencing the gene triggers ...
Scientists Identify HERC4 as the Molecular Switch That Turns TNF Survival Signals Into Cell Death
Researchers have discovered that the protein HERC4 acts as the critical molecular switch that converts TNF survival signalling into cell ...
Virus-driven lymphoma cells rely on a mitochondrial enzyme duo to dodge cell death
New research reveals that the mitochondrial ubiquitin ligase MARCHF5 helps KSHV-transformed lymphoma cells survive by degrading NOXA, the natural antagonist ...
Mutant Tau Pushes the Cell’s Protein Factory into Overdrive, Study Finds
New research in Translational Psychiatry shows that disease-associated MAPT mutations drive tau accumulation in the nucleolus, hyperactivating ribosomal DNA transcription ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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