Infection by the microsporidian parasite Enterocytozoon hepatopenaei damages mitochondrial structure, elevates reactive oxygen species, and shifts metabolic and apoptotic pathways ...
Extract from Chloroxylon swietenia demonstrated significant dose-dependent cytotoxicity, induced apoptosis, and suppressed tumour growth in glioblastoma models.
Targeting PARP and SHP2 pathways simultaneously overcame therapy resistance and slowed tumor growth in preclinical models of advanced breast cancer.
A prospective cohort study of Chinese women found lower baseline erythrocyte folate associated with increased persistence and progression of low-grade ...
Preclinical experiments demonstrate that OXSR1 deficiency attenuates ischemia-reperfusion-induced acute kidney injury and oxidative stress by inactivating the JAK2/STAT3 pathway.
Pectolinarigenin inhibits colorectal cancer cell growth and progression by downregulating glycolytic enzymes and modulating AMPK/FOXO3a signaling pathways in preclinical models.
Researchers have synthesized a 1-aminopyridine-stabilized gold and reduced graphene oxide nanocomposite that enhances dispersibility and induces apoptotic cell death in ...
A narrative review concludes that host vascular and immune accessibility, rather than nucleus pulposus cell death alone, shapes whether herniated ...
In vitro experiments reveal that melatonin promotes cashmere goat dermal papilla cell proliferation by downregulating chi-miR-1388-3p to relieve repression of ...
Researchers found that the protein DJ-1 promotes glioblastoma progression through the UBA52-mediated NF-κB signaling pathway in cell and mouse models.
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