Caesalpinia spinosa extract selectively affects mouse colorectal cancer cells
A standardized Caesalpinia spinosa extract reduced viability in mouse colorectal cancer cells alongside increased reactive oxygen species and caspase activation, ...
Tag: apoptosis
Coagulation-associated genes stratify acute myeloid leukemia and spotlight SPINT2
An integrated transcriptomic and laboratory study linked coagulation-associated gene activity to survival and immune states in acute myeloid leukemia, while ...
Chilli extract shows preclinical activity against lung adenocarcinoma in rats
A chemically complex chilli-pepper extract reduced proliferation, inflammation and oxidative-stress markers in a DEN-induced rat model of lung adenocarcinoma, with ...
GFPT1 silencing curbs aggressive esophageal cancer cell behavior through ER stress
Cell experiments found that silencing GFPT1 reduced proliferation, migration and invasion in esophageal cancer cells, with a rescue experiment supporting ...
Radiation suppresses PiC, triggering mitochondrial dysfunction and glioma cell death
A mechanistic study in glioma cells and mouse tumor models links radiation-induced PiC suppression to mitochondrial dysfunction, sustained pore opening, ...
Targeting pyroptosis in intestinal and systemic inflammatory diseases: mechanisms and therapeutic opportunities
A 2026 review identifies pyroptosis as a context-dependent pathway in intestinal and systemic inflammation and evaluates inflammasome, caspase and gasdermin-directed ...
Machine learning and cell study link shikonin to Parkin-dependent activity in hypoxic triple-negative breast cancer
A machine-learning and cell-culture study found that shikonin induced necroptosis and apoptosis in hypoxic MDA-MB-231 breast cancer cells through a ...
Research report: HIV-1 Vpr: a multifunctional accessory protein with potential contributions to AIDS pathogenesis and persistence
A 2026 review concludes that HIV-1 accessory protein Vpr coordinates cell-cycle arrest, mitochondrial death, immune signaling and viral replication, but ...
Systematic review of 14 in vitro studies links natural products to apoptosis in salivary gland mucoepidermoid carcinoma
A systematic review of 14 in vitro studies found that natural products showed antiproliferative and proapoptotic activity in human mucoepidermoid ...
PD-L1-targeted nanosystem shows antitumor activity in triple-negative breast cancer cell and mouse models
A cell and mouse study found that a PD-L1-targeted silver, doxorubicin and manganese dioxide nanosystem increased particle uptake and produced ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!