RNA Methylation Enzyme METTL16 Emerges as Guardian of Rod Photoreceptor Survival
New research shows that the RNA methyltransferase METTL16 protects rod photoreceptors by safeguarding splicing fidelity, mRNA stability, and translation, and ...
Tag: alternative splicing
Graph Neural Network GLASS Cleans Up Long-Read RNA Sequencing Alignments
A new graph neural network method called GLASS filters unreliable splice alignments in long-read RNA sequencing data, improving the precision ...
RNA Splicing Errors in Drug Transporter Genes May Predict Cancer Survival Across 33 Tumor Types
A sweeping multi-omics study links alternative splicing of ABC transporter genes to survival across 33 cancer types and confirms causal ...
One Phosphate Switch Decides How a Plant Splicing Factor Fights Salt Stress
A new study shows that phosphorylation of a single threonine residue in the Arabidopsis splicing factor SR45.1 controls nuclear speckle ...
Faulty RNA Splicing of SCARB1 Linked to Metabolic Collapse in Early Pregnancy Loss
A new study links dysregulated alternative splicing of the cholesterol receptor gene SCARB1, potentially controlled by the transcription factor TEAD4, ...
Motor Protein KIFC1 Fuels Cervical Cancer Radioresistance Through a Splicing-Driven Glycolytic Switch
New research reveals that the motor protein KIFC1 drives cervical cancer radioresistance by shuttling the splicing factor SRSF3 into the ...
Loss of a Single Splicing Protein Reshapes the Heart’s Scarring Response
Deleting the RNA splicing factor PTBP1 in cardiac fibroblasts reshapes the profibrotic response by altering alternative splicing of key fibrosis-related ...
Splicing Factor BRR2a Keeps Plant Stress Genes Silent Until Trouble Hits
New research shows the essential splicing factor BRR2a doubles as a repressor that keeps stress-inducible genes silent in Arabidopsis until ...
New Sequencing Method Maps RNA Isoforms Across Brain Cells With Single-Cell Precision
A new Nature Methods study introduces spatial isoform sequencing tools that reveal cell-type-specific RNA isoform variability across mouse brain tissue ...
Body Clock Protein BMAL1 Steers Stem Cells Into Neurons Through RNA Tagging
A new study in Genome Biology shows that the circadian factor BMAL1 is required for human embryonic stem cells to ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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