Motor Protein KIFC1 Fuels Cervical Cancer Radioresistance Through a Splicing-Driven Glycolytic Switch
New research reveals that the motor protein KIFC1 drives cervical cancer radioresistance by shuttling the splicing factor SRSF3 into the ...
Tag: alternative splicing
Loss of a Single Splicing Protein Reshapes the Heart’s Scarring Response
Deleting the RNA splicing factor PTBP1 in cardiac fibroblasts reshapes the profibrotic response by altering alternative splicing of key fibrosis-related ...
Splicing Factor BRR2a Keeps Plant Stress Genes Silent Until Trouble Hits
New research shows the essential splicing factor BRR2a doubles as a repressor that keeps stress-inducible genes silent in Arabidopsis until ...
New Sequencing Method Maps RNA Isoforms Across Brain Cells With Single-Cell Precision
A new Nature Methods study introduces spatial isoform sequencing tools that reveal cell-type-specific RNA isoform variability across mouse brain tissue ...
Body Clock Protein BMAL1 Steers Stem Cells Into Neurons Through RNA Tagging
A new study in Genome Biology shows that the circadian factor BMAL1 is required for human embryonic stem cells to ...
Alcohol Withdrawal Reshapes RNA Binding of PCBP1 in the Hippocampus
A new RIP-Seq study reveals sex-dependent changes in how the RNA-binding protein PCBP1 associates with synaptic and myelination-related transcripts in ...
Soluble receptor variants fine-tune placental blood vessel growth, study finds
A new study shows that soluble PDGFRβ isoforms, produced under hypoxic conditions in the developing placenta, act as feedback modulators ...
Alternative splicing could reveal proteins’ hidden functions
A new computational study is turning the spotlight on one of biology’s most difficult questions: why can two protein isoforms ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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