A Single Botched Splice May Explain a Deadly Yellow-Leaf Soybean Mutant
Fine mapping of a soybean yellow-leaf lethal mutant has narrowed the cause to a 165-kilobase region on chromosome 10, where ...
Tag: alternative splicing
RNA-Binding Protein HuR Emerges as a Master Switch in Tau Splicing and Alzheimer’s Genes
A new study identifies the RNA-binding protein HuR as a repressor of tau exon 10 splicing and a regulator of ...
Tiny genetic switches: how microexons quietly rewire where proteins live in our cells
A new study shows that alternative splicing, especially through microexons shorter than five amino acids, fine-tunes protein interaction interfaces to ...
Hidden poison exons in the human brain reveal a new route into neurological disease
A genome-wide study identifies 9,814 poison exons in the human genome and shows that hundreds are brain-specific, linking their mis-splicing ...
How a Heat-Loving Plant Rewires Its RNA to Survive Scorching Temperatures
New research on the heat-tolerant shrub Rhododendron hainanense shows that escalating temperatures trigger a surge in alternative splicing that diversifies ...
One Gene, Two Proteins: Why CFH Cancer Biomarker Studies May Be Measuring the Wrong Molecule
A new commentary in BMC Cancer warns that pan-cancer studies treating CFH as a single cancer biomarker have been measuring ...
Rare Fusion Gene and WT1 Overexpression Define an Aggressive Leukemia Subtype
A newly reported leukemia case carrying both the rare DEK::CAN fusion gene and WT1 overexpression reveals how genetic synergy and ...
Blocking the Brain’s Cannabis Receptor Repairs Faulty RNA Splicing in Fragile X Mice
A new study in iScience shows that blocking the cannabinoid CB1 receptor with low-dose rimonabant reverses disease-associated alternative splicing defects ...
Long-Read RNA Sequencing Reveals Hidden Isoform Chaos That Gene-Level Cancer Studies Miss
A long-read RNA sequencing atlas of 144 paired tumor-normal samples across ten organs shows that gene expression changes converge across ...
Fly Study Reveals How the RNA Modifier Mettl16 Shapes Development and Fertility
New research in fruit flies shows that the RNA methyltransferase Mettl16 is dispensable for survival but essential for fertility, acting ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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