Three Guduchyadi phytochemicals remain bound in MCI-related protein simulations
A computational study identified 368 putative compounds in Guduchyadi Yoga and modeled persistent binding by three selected phytochemicals to AKT1, ...
Tag: AKT1
Network and cell study links carboplatin to four melanoma targets
Network analysis and B16F0 cell experiments linked carboplatin with CDKN1A, BRCA1, PTEN and AKT1 in melanoma, without establishing clinical benefit.
Research report: Genome-wide association study identifies PPP2R2B as a modifier of positive symptom improvement in schizophrenia patients treated with aripiprazole
A six-week genome-wide association study found that the single-nucleotide polymorphism rs2125443 in PPP2R2B was significantly associated with improvement in positive ...
Buckwheat Compound Fagopyrine Emerges as Computational Lead for AKT1 Cancer Drug Design
A pan-cancer computational study identified the buckwheat-derived compound fagopyrine as a strong predicted binder to the AKT1 kinase, positioning it ...
Traditional Cough Remedy Decoded: How Zhike Pipa Granules Fight Bronchitis at the Molecular Level
Researchers combined mouse experiments, network pharmacology, and molecular docking to show that the traditional Chinese medicine Zhike Pipa Granules relieve ...
Citrus Flavonoid Meets Nuclear Medicine in Twin Radiometal Design for Breast Cancer
Computational simulations show that the citrus flavonoid hesperidin can be paired with technetium for imaging and rhenium for therapy, with ...
Aluminum Oxide Nanoparticles Trigger a Nonlinear Stress Response in the Biofuel Crop Camelina
A new study finds that aluminum oxide nanoparticles show a nonlinear dose-dependent effect on the biofuel crop Camelina sativa, promoting ...
Tea Compounds Show Surprising Power Against Cancer and Aging Proteins
A new network pharmacology study identifies 14 tea phytochemicals that strongly bind the cancer- and metabolism-linked hub proteins PIK3CA, AKT1, ...
Gut Microbe Metabolites May Reach Bone Cells Through an AKT1 Signaling Network
A new computational framework traces candidate routes from specific gut bacteria and their metabolites to osteoporosis-related signaling hubs, with independent ...
Microwave Method Turns Shrimp Shell Waste Into Wound-Healing Chitosan
A microwave-assisted extraction method produces higher-yield, higher-quality chitosan from shrimp shell waste with up to 94.6 percent less energy than ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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