Hidden Gene Variants May Explain Why Chemotherapy Hits Some Patients Harder Than Others
A new review links inherited variants in ABCB1, ABCC1, and ABCG2 drug transporter genes to differences in chemotherapy and targeted ...
Tag: ABC transporters
Old Drugs, New Tricks: How Repurposing Could Crack Cancer’s Resistance Problem
A new review in Molecular Cancer maps how approved drugs from outside oncology could be repurposed, under a strict mechanism-first ...
Marine bacterium reveals its full molecular playbook for devouring bioplastic
Researchers at Savitribai Phule Pune University have mapped the complete gene-level mechanism by which the marine bacterium Nocardiopsis dassonvillei NCIM ...
Gut Bacterium Yields 41 Protein Clues in Hunt for Colorectal Cancer Fighters
Researchers used activity-guided fractionation and proteomics to identify 41 secreted protein candidates from a non-enterotoxigenic Bacteroides fragilis strain associated with ...
Crippling a Hormone Export Route Gives Crops Immunity to Witchweed
New research shows that editing strigolactone transporter genes in sorghum and tomato can suppress parasitic weeds by up to 94 ...
RNA Splicing Errors in Drug Transporter Genes May Predict Cancer Survival Across 33 Tumor Types
A sweeping multi-omics study links alternative splicing of ABC transporter genes to survival across 33 cancer types and confirms causal ...
Metal stress rewrites plant DNA methylation within minutes, review finds
A new review in Ecotoxicology shows that plants respond to heavy metal toxicity with rapid, targeted DNA methylation changes that ...
ABC Transporter Gene ABCG2 Emerges as a Dynamic Marker of Acute Pancreatitis Severity
A prospective clinical study finds that ABCG2 gene expression is suppressed in acute pancreatitis patients yet rises significantly with radiologically ...
Castration Reshapes Meat Quality and Muscle Metabolites in Black Tibetan Sheep
A new metabolomics study shows that castration improves water retention, texture, and amino acid and fatty acid levels in Black ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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