About The Study: This study including 903 women with BRCA germline pathogenic variants found that a breast cancer diagnosis less than 10 years postpartum was associated with higher risk of mortality compared with nulliparous women and women diagnosed at least 10 years postpartum. These results should inform genetic counseling, prevention, and treatment strategies for BRCA pathogenic variant carriers.
About The Study: This study including 903 women with BRCA germline pathogenic variants found that a breast cancer diagnosis less than 10 years postpartum was associated with higher risk of mortality compared with nulliparous women and women diagnosed at least 10 years postpartum. These results should inform genetic counseling, prevention, and treatment strategies for BRCA pathogenic variant carriers.
Authors: Zhenzhen Zhang, Ph.D., of Oregon Health & Science University in Portland, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.7421)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Cite Scienmag News
Nathaniel Bowman. (April 19, 2024). Postpartum breast cancer and survival in women with germline BRCA pathogenic variants. Scienmag. https://scienmag.com/postpartum-breast-cancer-and-survival-in-women-with-germline-brca-pathogenic-variants/
Nathaniel Bowman. "Postpartum breast cancer and survival in women with germline BRCA pathogenic variants." Scienmag, 19 April 2024, https://scienmag.com/postpartum-breast-cancer-and-survival-in-women-with-germline-brca-pathogenic-variants/. Accessed 5 September 2026.
Nathaniel Bowman. "Postpartum breast cancer and survival in women with germline BRCA pathogenic variants." Scienmag. April 19, 2024. https://scienmag.com/postpartum-breast-cancer-and-survival-in-women-with-germline-brca-pathogenic-variants/
