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Clemson University bioengineer and Amgen industry partners to develop a controls-oriented metabolic model for Chinese hamster ovary cells

June 28, 2024
in Technology and Engineering
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Clemson University bioengineer and Amgen industry partners to develop a controls-oriented metabolic model for Chinese hamster ovary cells
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Academic and industry partnership led by Sarah Harcum, a Professor in the Department of Bioengineering in Clemson University, seeks to enhance the accuracy of oxygen uptake rate estimation of Chinese hamster ovary (CHO) cells which are the primary mammalian cell lines use to develop pharmaceuticals. In addition, this collaborative  team plans to develop tools to differentiate cell metabolism from other physical system changes, construct a mathematical model of cell behavior to improve CHO cell productivity, and develop curriculum modules to enhance students and industry collaborations. This new project is jointly funded by the National Science Foundation (NSF) and the Established Program to Stimulate Competitive Research (EPSCoR).

Academic and industry partnership led by Sarah Harcum, a Professor in the Department of Bioengineering in Clemson University, seeks to enhance the accuracy of oxygen uptake rate estimation of Chinese hamster ovary (CHO) cells which are the primary mammalian cell lines use to develop pharmaceuticals. In addition, this collaborative  team plans to develop tools to differentiate cell metabolism from other physical system changes, construct a mathematical model of cell behavior to improve CHO cell productivity, and develop curriculum modules to enhance students and industry collaborations. This new project is jointly funded by the National Science Foundation (NSF) and the Established Program to Stimulate Competitive Research (EPSCoR).



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