Medicine
Structure Reveals How Crimean-Congo Hemorrhagic Fever Virus Polymerase Is Inhibited
Crimean–Congo haemorrhagic fever virus (CCHFV), a tick-borne pathogen, continues to threaten public health with severe and often fatal human disease....
Immunological Misadaptation Predicts Spontaneous Preterm Birth in Pregnancies
A new study in Nature Communications suggests that the immune system’s “miscalibration” may begin well before the first clinical signs...
How Extracellular Histones Disrupt Cardiomyocyte Function: New Mechanisms
A team studying how blood-borne danger signals harm the heart has traced a new pathway linking extracellular histones to cardiomyocyte...
Simulation Boot Camp Improves Neonatal Critical Care Skills for Senior Fellows
Neonatal-Perinatal Medicine (NPM) fellowships are built to prepare physicians for high-stakes care at the edge of viability, where rapid decisions...
Azacitidine and Venetoclax Impact Inflammatory Markers and Response in Elderly AML
A new study highlights how a two-drug strategy may reshape inflammatory biology in older adults newly diagnosed with acute myeloid...
Empagliflozin and Other SGLT2 Inhibitors Show Cardioprotective Benefits
Since the landmark EMPA-REG OUTCOME trial, sodium–glucose cotransporter 2 (SGLT2) inhibitors have rapidly shifted from diabetes drugs to a central...
Recombinase-Based Genome Mapping Enables Large-Scale Structure Profiling of Prime Edits
A new protocol promises to turn the static architecture of mammalian genomes into something far more experimentally tractable. Understanding how...
Urinary Microbiome Links to Overactive Bladder, Pain Syndrome, and New Therapies
New research is reshaping how clinicians think about lower urinary tract disorders by challenging the long-held assumption that urine is...
Active Learning Aids Design of Fiber Gut Microbiome Interactions
A new study is spotlighting an ambitious goal for gut-health precision medicine: figuring out which dietary fibers selectively encourage beneficial...
Study Shows Dengue Virus Infects Immune Cells Designed to Prevent Infection
Researchers at the University of Vermont Robert Larner, M.D. College of Medicine and Upstate Medical University report that dengue virus...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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