Biology
Infant Gut Microbes and Diet-Derived Metabolites Linked to Childhood Asthma Risk
An exploratory study of a Tennessee birth cohort links infant gut bacteria and diet-derived lipid metabolites to asthma diagnosed at...
Hydrogels Bring Tumors to Life in the Lab, Reshaping Cancer Research
A new review details how hydrogel-based 3D platforms are transforming cancer research by recreating the tumor microenvironment for drug testing,...
Epigenetic Editing Steps Closer to the Clinic as Bioengineering Tools Mature
The EpiBio-24 conference in Amsterdam showcased maturing epigenetic engineering tools, durable gene silencing in animal models, and growing clinical momentum...
Reprogramming Patient Cells Reveals a Reversible Signalling Flaw Behind a Childhood Hip Disease
A patient-derived stem cell model shows that hyperactive GSK3 signalling suppresses bone, fat and cartilage differentiation in Legg-Calvé-Perthes disease, and...
Approved Metabolism Drugs Rescue Disease Signs in SMA Mice
Three commercially approved metabolism-targeting drugs—pioglitazone, melatonin and insulin—improved survival, motor function, muscle size and hepatic pathology in Smn2B/- spinal muscular...
Vitamin D Receptor Gene Variants Tied to Diabetic Foot Ulcer Risk in Kerala Study
A new study from Kerala, India, links two vitamin D receptor gene variants and vitamin D deficiency to the risk...
Engineered mini CRISPR enzyme gets a 60-fold power boost for gene editing
Researchers transformed the inactive compact nuclease CgCas12n into a high-efficiency genome and base editor through arginine enrichment and guide RNA...
Tiny Wheat Germ Oil Capsules Rescue Fat-Free Goat Yogurt’s Texture and Vitamin E
Scientists fortified non-fat goat yogurt with wheat germ oil microparticles stabilized by modified starch and wheat gluten protein hydrolysate, restoring...
Machine Learning and Molecular Scaffolds Supercharge Production of a Licorice-Derived Drug Molecule
Researchers combined machine learning-guided optimization with self-assembling protein scaffolds in a cell-free enzyme system to boost liquiritigenin production to 439...
Blocking the Growth Hormone Receptor Extends Mouse Lifespan, Landmark Study Finds
A formal aging study of 351 mice shows for the first time that blocking the growth hormone receptor with an...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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