Cryo-EM Reveals Biopsy-Derived TTR Fibril Structures in Hereditary Amyloidosis
Hereditary transthyretin amyloidosis (hATTR) is driven by the misfolding of transthyretin (TTR), a transport protein whose fragments assemble into toxic...
AI-Guided Handheld Cardiac Ultrasound Promises Early Detection and Cost Savings
Handheld ultrasound is moving from hospitals to the bedside. A new study published in The Annals of Family Medicine reports...
Mitophagy dampens mitochondrial DNA–triggered cGAS-STING activation in autoimmune thyroiditis
Viral science news: Autoimmune thyroiditis has long puzzled researchers with how mitochondrial material sparks an inflammatory cascade that ultimately damages...
Navigation Service Outperforms Signposting for Linking Primary Care Patients to Resources
A new randomized trial published in The Annals of Family Medicine tests a simple but powerful idea: when patients struggle...
Immunological Misadaptation Predicts Spontaneous Preterm Birth in Pregnancies
A new study in Nature Communications suggests that the immune system’s “miscalibration” may begin well before the first clinical signs...
How Extracellular Histones Disrupt Cardiomyocyte Function: New Mechanisms
A team studying how blood-borne danger signals harm the heart has traced a new pathway linking extracellular histones to cardiomyocyte...
Empagliflozin and Other SGLT2 Inhibitors Show Cardioprotective Benefits
Since the landmark EMPA-REG OUTCOME trial, sodium–glucose cotransporter 2 (SGLT2) inhibitors have rapidly shifted from diabetes drugs to a central...
Macrophage Adenylyl Cyclase 7 Shields Male Mice From Ischemia-Reperfusion Injury
A new study from Nature Communications highlights an unexpected immune target in the heart’s response to injury. Researchers report that...
Nonclassical biosynthetic pathway allows bacteria to synthesize tocopherol
Microbial production of tocopherols—key forms of vitamin E used in healthcare, medicine, and animal nutrition—has long been limited by incomplete...
APREAL Fall-Prevention Program Improves Safety for Hospitalized Elderly Patients
In today’s viral science news, researchers report encouraging evidence that a structured, participatory fall-prevention education program—known as APREAL—can reduce fall...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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