About The Study: In critically ill sepsis patients, treatment with intravenous acetaminophen for 5 days was safe but did not improve the primary end point of days alive and free of any organ support (dialysis, assisted ventilation, and vasopressors) to day 28 compared with placebo.
About The Study: In critically ill sepsis patients, treatment with intravenous acetaminophen for 5 days was safe but did not improve the primary end point of days alive and free of any organ support (dialysis, assisted ventilation, and vasopressors) to day 28 compared with placebo.
Corresponding Author: To contact the corresponding author, Lorraine B. Ware, M.D., email Lorraine.ware@vumc.org.
To access the embargoed study: Visit our For The Media website at this link
(doi:10.1001/jama.2024.8772)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the American Thoracic Society 2024 International Conference.
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Journal
JAMA
Cite Scienmag News
Ophelia Keating. (May 19, 2024). Acetaminophen for prevention and treatment of organ dysfunction in critically ill patients with sepsis. Scienmag. https://scienmag.com/acetaminophen-for-prevention-and-treatment-of-organ-dysfunction-in-critically-ill-patients-with-sepsis/
Ophelia Keating. "Acetaminophen for prevention and treatment of organ dysfunction in critically ill patients with sepsis." Scienmag, 19 May 2024, https://scienmag.com/acetaminophen-for-prevention-and-treatment-of-organ-dysfunction-in-critically-ill-patients-with-sepsis/. Accessed 3 September 2026.
Ophelia Keating. "Acetaminophen for prevention and treatment of organ dysfunction in critically ill patients with sepsis." Scienmag. May 19, 2024. https://scienmag.com/acetaminophen-for-prevention-and-treatment-of-organ-dysfunction-in-critically-ill-patients-with-sepsis/
