Leading scholarly publisher and innovative technology provider Pensoft has embarked on a pioneering venture by launching the Journal of Regeneration (JoR), an open-access, peer-reviewed publication designed to bring forth a holistic and multidisciplinary perspective on regenerative biology. This ambitious new journal aims to unify science across a remarkable breadth of life forms—from plants to animals—and across a wide spectrum of fields, including developmental biology, evolutionary studies, ecology, agriculture, and cutting-edge medical research. By doing so, JoR aims to deepen our understanding of the fundamental biological processes that govern regeneration, the innate ability of organisms to repair, restore, and renew tissues, organs, and indeed entire body structures following injury or damage.
The need for such a transversal platform arises from the realization that regeneration is a trait not confined to well-studied model organisms or narrow disciplines, but rather a universal phenomenon exhibiting common cellular and molecular themes across kingdoms. By fostering scientific discourse that traverses traditional boundaries, JoR facilitates the sharing of insights into cellular plasticity—the capacity of cells to adopt different fates—and the signaling pathways activated in response to injury. In particular, this includes elucidating injury-triggered cascades that orchestrate cellular responses, as well as the epigenetic modifications that reset cellular potential during regeneration, thereby providing essential clues applicable to both fundamental biology and translational medicine.
The scope of the journal is rigorously comprehensive, integrating research from the molecular and genetic level all the way to clinical implications and applications. Articles will encompass investigations employing cutting-edge technologies including single-cell transcriptomics, which allows unprecedented resolution of gene expression at an individual cell level; CRISPR/Cas9 genome editing, revolutionizing the functional dissection of regenerative pathways; advanced transgenic models to track cell lineage and fate; and sophisticated mass spectrometry approaches to map proteomic landscapes during regrowth processes. This inclusive approach ensures that JoR remains at the forefront of methodological innovation, providing a vital conduit for research that informs regenerative biology at both ecological and biomedicine interfaces.
At the conceptual core of JoR lies the ambition to support long-term research themes that have profound implications for human health and biology. These include systems-level understanding of regenerative networks, exploring the evolutionary biology underlying varied regenerative capacities among species, as well as bioengineering strategies to mimic or enhance natural regenerative phenomena. One particularly promising direction is the intersection of ageing and regeneration, a field gaining momentum as scientific advances reveal intricate molecular links between tissue renewal and lifespan regulation. This nexus holds transformative potential for regenerative medicine, promising therapeutic strategies for age-related degenerative diseases.
The distinguished editorial leadership of JoR represents an international alliance of preeminent experts dedicated to advancing the field of regenerative biology. Among them, Dr. Anna Czarkwiani of Technische Universität Dresden envisions the journal as an indispensable forum where researchers can proactively exchange ideas, resources, and innovations. Prof. Loriano Ballarin from the Università degli Studi di Padova emphasizes the journal’s role in forging dialogue across diverse subfields of regeneration science, recognizing that only through such interdisciplinary conversations can the field achieve meaningful breakthroughs. Meanwhile, Prof. Baruch Rinkevich of the Israel Oceanographic and Limnological Research Institute envisions JoR as a vibrant venue uniting diverse biological perspectives to unravel life’s intrinsic ability to rebuild and redefine itself iteratively.
The Journal of Regeneration benefits from Pensoft’s ARPHA platform, a state-of-the-art manuscript submission and publishing ecosystem. ARPHA provides a seamless, fully integrated publishing experience that supports every stage of the scientific communication pipeline—from manuscript submission and rigorous peer review to publication, indexing, and permanent archiving. This robust infrastructure not only expedites the dissemination of high-quality research but also ensures discoverability and long-term accessibility, hallmarks of modern scientific publishing. Notably, to encourage early submissions and foster community engagement, JoR offers free article processing during its initial launch phase, removing financial barriers and ensuring broad participation from the global regeneration research community.
This new journal emerges at a pivotal time when regeneration research itself is undergoing rapid transformation—moving beyond isolated descriptive studies toward mechanistic understanding and active harnessing of regenerative processes for therapeutic ends. JoR’s foundational premise—that understanding regeneration demands an integrative approach spanning the full spectrum of life sciences—sets it apart from more conventional journals. It encourages submissions that explore principles shared across taxonomic domains and those that apply sophisticated experimental tools to decipher cellular fate decisions, molecular signaling, and system-wide regenerative events under both physiological and pathological conditions.
By elevating regeneration research within an open-access, multidimensional format, JoR is poised to accelerate paradigm shifts in biology and medicine. It invites contributions that bridge laboratory and field studies, translate discovery into clinical innovation, and rethink longstanding concepts about cellular plasticity and tissue dynamics. Such integration is critical to overcoming the current challenges faced in regenerative medicine, including scalability, safety, and functional integration of regenerated tissues.
The journal also welcomes studies employing emerging technologies such as lineage tracing combined with spatial transcriptomics, which map regenerative processes within their native tissue architecture—offering spatially contextualized insights into cellular heterogeneity and niche microenvironments. Complementary omics technologies, from proteomics to metabolomics, are encouraged to dissect the complex biochemical milieu that supports regeneration, illuminating novel targets for bioengineering and therapeutic intervention.
Moreover, JoR is particularly interested in adaptive and evolutionary perspectives, exploring how diverse species have evolved regenerative capacities in response to environmental pressures. Such comparative biology approaches provide a fertile context to identify conserved mechanisms and molecular “toolkits” that might be leveraged in more regenerative-impaired species, including humans.
As the field rapidly evolves, fostering open collaborative networks and data-sharing initiatives is central to JoR’s vision. Integrating experimental data with computational modeling and systems biology approaches, the journal serves as an intellectual hub where theoretical frameworks meet empirical findings, catalyzing innovative hypotheses and translational breakthroughs.
In all, the Journal of Regeneration stands to become a landmark publication that not only chronicles ongoing advances but also actively shapes the future of regenerative science. By fostering a collaborative, cross-disciplinary culture embedded in technological innovation and scientific rigor, JoR will empower researchers globally to unveil the secrets of life’s remarkable capacity to restore itself, ultimately contributing to the development of regenerative therapies that may revolutionize healthcare.
Subject of Research: Regenerative biology and interdisciplinary approaches across species.
Article Title: Pensoft Launches the Journal of Regeneration: A Multidisciplinary Platform Connecting Biology and Medicine.
News Publication Date: Not specified in the original content.
Web References:
https://pensoft.net/
https://regeneration.pensoft.net/
https://arphahub.com/
http://dx.doi.org/10.3897/regeneration.1.196461
Image Credits: Pensoft Publishers
Keywords: Regeneration, developmental biology, cellular plasticity, molecular genetics, epigenetics, CRISPR/Cas9, single-cell transcriptomics, bioengineering, ageing, evolutionary biology, ARPHA platform, regenerative medicine
