NFAT Transcription Factors Emerge as Central Drivers of Pulmonary Hypertension
A new review in Molecular Biology Reports synthesizes evidence that NFAT1-4 transcription factors drive the abnormal proliferation of pulmonary artery ...
Tag: vascular remodeling
Male mice fare worse after heart radiation, revealing sex differences in cardiac injury
A Mayo Clinic study of irradiated mice shows that males develop inflammatory dilated cardiomyopathy and fibrosis after cardiac radiation while ...
Hedgehog-Responsive Perivascular Cells Emerge as Master Switches of Blood Vessel Repair and Disease
A new review synthesizes a decade of evidence showing that GLI1-positive perivascular cells act as state-dependent regulators of angiogenesis, capable ...
Chromatin protein CBX3 emerges as a promising biomarker for cardiovascular disease
A new review highlights how the chromatin protein CBX3 regulates vascular smooth muscle behavior, inflammation, and cancer-related pathways, positioning it ...
Astrocyte Enzyme PHGDH Drives Blood Vessel Repair After Stroke
New research shows that the astrocytic enzyme PHGDH supplies serine to growing brain vessels through endothelial SLC38A2 transport and mTORC1 ...
Immune Cells Cleared in Mouse Hypertension Mystery, but Human Evidence Points to RGS2
A new mouse study finds that deleting RGS2 in myeloid cells does not affect angiotensin II-induced hypertension or organ damage, ...
Cell Power Plants Emerge as New Suspects in Birth Defect That Cripples Lungs
A new study links altered energy metabolism in endothelial cells to the lung and vascular complications of congenital diaphragmatic hernia.
Blood Vessels May Hum at High Frequencies, and Those Vibrations Could Drive Vascular Disease
Researchers report that disturbed blood flow can make vessel walls vibrate at high frequencies, and that these vibrations may directly ...
Veins Take the Lead: Landmark Study Reveals How Human Arteries and Veins Rebuild After Devastating Leg Trauma
A prospective Finnish study of 40 trauma patients shows that intimal hyperplasia develops within days of severe leg injury and ...
Review outlines emerging directions in pulmonary arterial hypertension research
Pulmonary arterial hypertension (PAH) is being redefined by molecular biology. Once viewed mainly as a disorder of excessive blood-vessel constriction, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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