Tiny Bubble Messengers Could Transform How Gastric Cancer Is Detected and Treated
A new review maps how extracellular vesicles drive gastric cancer progression and how engineered versions could become diagnostics and drug ...
Tag: tumor microenvironment
Self-Reporting Nanoparticle Turns Tumor Hypoxia Into a Weapon Against Cancer
Researchers have created a chemiluminescent nanoparticle that amplifies tumor hypoxia with light, releases a chemotherapy drug in response, and glows ...
Meningioma Study Points to CD73 as a Candidate Biomarker of Tumor Grade
An exploratory Brazilian study of 40 surgically resected meningiomas found that CD73 expression rises while PD-L1 falls in WHO grade ...
Rare IL-15-Driven NK Cell Subset Supercharges T Cell Attack on Melanoma
Researchers have identified a bone marrow-derived CD11c-positive B220-positive NK cell subset selectively expanded by IL-15 that outperforms conventional NK cells ...
Lactate-Fueled Tumor Neighborhoods: Glycolysis Hotspots Recruit Neutrophils in Lung Cancer
A multi-omics study maps lactate-glycolysis activity in lung adenocarcinoma to fibroblasts and neutrophils, revealing spatially organized metabolic niches linked to ...
Stroke Injury May Rewire the Brain in Ways That Accelerate Glioma Growth
New research in Nature Cancer shows that ischemic stroke reshapes the brain's tumor microenvironment, reducing calcium signaling in astrocytes through ...
How Immunotherapy Is Rewriting the Rules of Liver Cancer Treatment
A sweeping review details how immune checkpoint inhibitors, combination regimens, CAR-T cells, vaccines, and oncolytic viruses are transforming treatment of ...
Engineered CAR-T Cells That Make Their Own IL-2 Show Stronger Staying Power Against Pancreatic Cancer
A preclinical study shows that CAR-T cells engineered to secrete an Fc-fused IL-2(C125S) variant persist longer, retain mitochondrial fitness, and ...
Dual-Target Radioligand INN02 Boosts Tumor Imaging and Therapy in Early Study
A new dual-targeting radioligand that binds both fibroblast activation protein and integrin αvβ3 showed sixfold higher tumor uptake than a ...
How Microbial Imbalances Shape Lung Cancer Growth and Treatment Failure
A new review details how microbial imbalances in the gut, airways, mouth, and tumors drive lung cancer progression and undermine ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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