How Microbial Imbalances Shape Lung Cancer Growth and Treatment Failure
A new review details how microbial imbalances in the gut, airways, mouth, and tumors drive lung cancer progression and undermine ...
Tag: tumor microenvironment
Chemotherapy-Free Drug Combo Shows Promise for Early Triple-Negative Breast Cancer
A phase II trial found that neoadjuvant camrelizumab plus apatinib, a chemotherapy-free combination of immunotherapy and anti-angiogenic therapy, produced manageable ...
Molecular Path Cleansers: Enzymes That Strip Tumor Defenses to Boost Immunotherapy
A new review details how enzymes that degrade the extracellular matrix and glycocalyx could open solid tumors to immune attack, ...
Immune Cell Resident Gene RBPJ Emerges as Key to Lung Cancer Immunotherapy Success
A new single-cell study identifies the transcription factor RBPJ and CD103-positive tissue-resident memory T cells as central drivers of successful ...
Cholesterol-Hungry Immune Cells May Decide Survival in Head and Neck Cancer
A multi-omics study finds that LDL cholesterol metabolism reshapes macrophages and tumor cells in head and neck squamous cell carcinoma, ...
Fat-Fueled RNA Signals Predict Survival and Drug Response in Lung Cancer
A new integrative study identifies three lipid metabolism-related long non-coding RNAs that predict survival, immune landscape, and drug sensitivity in ...
Dogs and Humans Share Genetic Drivers of Liver Cancer, First Multi-Omics Study Reveals
A first-of-its-kind multi-omics study shows that dogs and humans share key genetic drivers and conserved tumor microenvironment features in hepatocellular ...
Cancer’s Hidden Helpers: Fibroblast Diversity Reshapes How Tumors Spread and How We Treat Them
A new review in Molecular Cancer maps the diverse states of cancer-associated fibroblasts and argues that precisely modulating, rather than ...
TGF-β2 Rewires Colon Cancer Cells to Survive Doxorubicin Through Autophagy and HMGB1
New research shows that the TGF-β2 signaling molecule steers metastatic colon cancer cells toward autophagy-mediated resistance to the chemotherapy drug ...
AI Reads Biopsy Slides to Predict Stomach Cancer Spread Before Surgery
A multicenter study reports that an ensemble deep learning model called LMRNet can predict lymph node metastasis in early gastric ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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