Gut Fungus Found Lurking in Prostate Tumors Speeds Cancer Growth in Mice
New research in Nature Cancer shows that the common commensal fungus Nakaseomyces glabratus is enriched in the feces and tumors ...
Tag: tumor microenvironment
METTL3 Emerges as a Molecular Hub Driving Tumor Immune Escape
A new review in the Journal of Translational Medicine details how the RNA methyltransferase METTL3 drives tumor immune escape through ...
RNA Acetylation Enzyme NAT10 Helps Glioblastoma Resist Radiotherapy
Researchers found that the RNA acetyltransferase NAT10 helps glioblastoma resist radiotherapy by stabilizing SLC7A11 mRNA and blocking immunogenic ferroptosis, and ...
Scientists Build a Gene-Based Survival Model for Lung Cancer Using a Newly Defined Cell Death Pathway
Researchers constructed a fourteen-gene triaptosis-related prognostic model for lung adenocarcinoma using transcriptomic analysis, machine learning, single-cell sequencing, and experimental validation.
Obesity Quietly Rewrites the Cellular Landscape of Colorectal Cancer Before Tumors Form
A dual-platform spatial transcriptomics study reveals that obesity reshapes colorectal cancer in two phases, first reprogramming healthy gut epithelium and ...
AI Maps a Hidden Neutrophil Niche in Lung Cancer and Flags a New Drug Target
A deep learning pipeline integrating single-cell and spatial transcriptomics has revealed an OSM-primed neutrophil niche that sustains aggressive mesenchymal tumor ...
Scientists Target the CD73-Adenosine Axis to Break Lung Cancer’s Immune Shield
A new review maps how the CD73-adenosine axis drives immune suppression in non-small cell lung cancer and how blocking it ...
Pericyte-like cells may help shape the immune landscape of glioblastoma
New research shows that FAP-positive pericyte-like cells in glioblastoma promote the differentiation of monocytes into immunosuppressive tumor-associated macrophages.
Blood Proteins May Reveal Who Benefits Most From Lung Cancer Immunotherapy
The prospective SARC-LUNG study links circulating immunometabolic biomarkers such as sRAGE and FGF21 with survival and immune microenvironment profiles in ...
Stress-Triggered RNA Molecule Helps Lung Cancer Cells Rewrite Their Fuel Supply
Researchers have identified an energy-stress-induced long non-coding RNA called GIRGL that drives glucose metabolism reprogramming in lung adenocarcinoma by interacting ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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