SPP1-Expressing Macrophages Predicted to Talk to T Cells in Breast Cancer Bone Metastases
A single-cell reanalysis of public datasets identifies an SPP1-expressing macrophage subset in breast cancer bone metastases and predicts its signaling ...
Tag: tumor microenvironment
MRI-Based Radiogenomic Model Predicts Survival in Glioblastoma via IL-19
A machine-learning radiogenomic model predicts IL19 expression from glioblastoma MRI scans and separates patients into survival groups.
DKK1 emerges as a multifunctional player in cancer progression
A new review consolidates evidence that the secreted protein DKK1 acts through multiple signaling routes and is associated with poor ...
How HPV rewires sugar chemistry in cervical cancer cells
A new review finds that O-GlcNAcylation links HPV-driven metabolic demand to growth and survival pathways in cervical cancer, but no ...
Review Explores Metabolic Reprogramming of Regulatory T Cells in Colorectal Cancer
A review in the Journal of Translational Medicine examines how metabolic reprogramming enables regulatory T cells to drive immunosuppression in ...
Advanced diffusion MRI reveals mismatch repair status of endometrial cancer before surgery
A prospective study found that time-dependent diffusion MRI microstructural parameters distinguished mismatch repair deficient from proficient endometrial cancer with an ...
Pyroptosis and Metabolism: How Cancer Cells Rewire Cell Death for Therapy
A new review maps how metabolic reprogramming controls gasdermin-mediated pyroptosis in tumors and outlines a four-level evidence framework for precision ...
Lactate-Driven Regulatory B Cells Suppress Immunity in Lung Cancer, Mouse Study Finds
A mouse and early human study links tumor-derived lactic acid to a ROS-producing regulatory B cell subset that suppresses T ...
AI-designed CAR binders push cancer stem cell immunotherapy toward safer targets
A new review maps how artificial intelligence could overcome resistance and safety barriers in cancer stem cell-targeted cellular immunotherapy, while ...
Secreted FGF Carriers Emerge as Prognostic Biomarkers Across Cancers
A new review maps how the three secreted FGFBP proteins tune FGF signaling in physiology and act as divergent prognostic ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!