T Cells Can Wipe Out Tumors Without Ever Recognizing Them
New research shows that activating bystander T cells inside tumors triggers antigen-independent tumor killing through cytokines, nitric oxide and innate ...
Tag: tumor microenvironment
Flavonoid Diosmetin Targets Endothelial Enzyme to Rewire Lung Cancer Immune Defenses
New research identifies endothelial CYP3A5 as a functional vulnerability in lung adenocarcinoma and shows that the natural flavonoid diosmetin suppresses ...
Neutrophils in Cancer: The Immune Cells That Turn Traitors and Healers
A comprehensive new review reveals how neutrophils, the immune system's most abundant white blood cells, are co-opted by tumors to ...
Bile Acids Emerge as Master Regulators Linking Gut Microbes, Immunity and Cancer
A new commentary in Holistic Integrative Oncology argues that bile acids act as master signaling molecules linking liver metabolism, gut ...
Tumor Vesicles Loaded with SPP1 Rewire Fibroblasts to Shield Lung Cancer from Immunity
New research shows that lung adenocarcinoma cells package the protein SPP1 into extracellular vesicles to reprogram fibroblasts into an MMP11-positive ...
Radium-223 Therapy Lowers PD-L1 in Prostate Cancer Bone Metastases, PET Study Shows
A prospective imaging study shows that radium-223 significantly reduces PD-L1 expression and depletes immune cells in prostate cancer bone metastases, ...
NINJ1: The Membrane-Rupturing Protein That Decides How Cells Die and How Tumors Thrive
A new review in the Journal of Cancer Research and Clinical Oncology examines how the NINJ1 protein executes plasma membrane ...
Neutrophil Traps That Feed Tumors: DNA Webs Emerge as Drivers and Markers of Cancer Progression
A new review details how neutrophil extracellular traps drive tumor growth, metastasis and treatment resistance while emerging as both biomarkers ...
Radiotherapy Reimagined as an Immune Weapon Against Pancreatic Cancer
A new perspective argues that radiation must be redesigned as an immunological platform to finally unlock the potential of combined ...
Engineered T Cell Receptors Push Into Solid Tumors as 2026 ASCO Data Offer Hope and Caveats
A critical review of eight studies from the 2026 ASCO Annual Meeting shows TCR-engineered T-cell therapy produced no treatment-related deaths ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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