Macrophage niches drive dormancy, EMT and chemoresistance in NSCLC stem cells
For years, cancer research has treated tumor cells as relatively stable enemies: cells that multiply, spread and acquire resistance through ...
Tag: tumor microenvironment
Scientists locate dormant cancer cells, revealing new treatment targets
Breast tumours may contain hidden “hibernation zones” where cancer cells stop dividing, evade chemotherapy and wait for an opportunity to ...
Spatial Transcriptomics Reveals Histology-Linked Growth Patterns in Colorectal Liver Metastases
A new study is turning the microscopic “how it grows” question in colorectal cancer liver metastases into a measurable molecular ...
Tertiary lymphoid structures contain stem-like tumor-specific T cells
Tertiary lymphoid structures (TLSs)—immune-cell aggregates that form in many solid tumours—have been linked to better outcomes from immune checkpoint blockade. ...
Local Complement C3 Shapes Control Myeloid Infiltration and Checkpoint Blockade Efficacy
A team investigating how tumors respond to immunotherapy reports that complement component C3 plays a decisive role—but only when it ...
Oncogene Inactivation–Triggered Senescence Enables Tumor Relapse
A new study in Nature Communications reveals how cancer cells can use the body’s own defenses against them. The work, ...
Single-Cell Multi-Omics Reveals Cancer-Associated Fibroblast Programs in Breast Cancer
A groundbreaking study has unveiled new insights into the complex biology of cancer-associated fibroblasts (CAFs) within triple-negative breast cancer (TNBC), ...
Polyvinyl chloride boosts liver cancer radioresistance by blocking CD8⁺ T cells
In a groundbreaking study that could have significant implications for cancer treatment, researchers have uncovered a surprising link between polyvinyl ...
Study shows lung tumors hijack nervous system to starve body
A groundbreaking study from NYU Langone Health and its Perlmutter Cancer Center elucidates a novel mechanism by which lung tumors ...
Decoding Ageing Tumor Microenvironment’s Genetic and Epigenetic Factors
As we navigate through life, our bodies continuously accumulate somatic mutations that lurk beneath the surface, quietly building a foundation ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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