How Stroke Injury Feeds the Brain’s Deadliest Tumors
A new Nature Cancer study shows that stroke remodels the brain's tumor microenvironment, creating tumor-associated astrocytes and macrophages that drive ...
Tag: tumor microenvironment
Six-Gene Signature Predicts Breast Cancer Prognosis and Immune Status
A new six-gene signature derived from weighted gene co-expression network analysis predicts breast cancer survival and characterizes the tumor immune ...
Scientists Map Two Distinct T Cell Exhaustion Programs Driving AML Relapse Before and After Transplant
Single-cell sequencing reveals that self-derived and donor-derived exhausted T cells in acute myeloid leukemia run on different transcriptional programs, with ...
Engineered Dendritic Cell Vaccine Draws Immune Cells Into Lung Tumors but Falls Short of Shrinkage
A phase I trial found that a CCL21-engineered dendritic cell vaccine combined with pembrolizumab safely increased T cell infiltration in ...
Hidden Immune Signal RSAD2 May Drive Endometrial Cancer Growth, Study Finds
A multi-omics study links the antiviral protein RSAD2 to CXCL1–CXCR1/2 signaling that recruits macrophages and drives endometrial cancer progression.
Bladder Cancer Protein GSDMB Boosts Immunotherapy by Recruiting Immune Cells
A new study reveals that the protein GSDMB enhances anti-PD-1 immunotherapy in bladder cancer by driving Sema7a-mediated recruitment and activation ...
Tiny Droplets Inside Cells Could Decide Whether Cancer Therapy Works
A new review in Molecular Cancer synthesizes how liquid-liquid phase separation shapes radiosensitivity, immune evasion, and treatment resistance in cancer.
Fibroblast collagen signal drives gut scarring and cancer in inflammatory bowel disease
A single-nuclei study reveals how CXCL14+ fibroblasts and SPP1+ macrophages form a collagen IV-driven feedback loop that promotes fibrosis and ...
ENO3 Emerges as a Lactate-Linked Biomarker in Colorectal Cancer Metastasis
Integrated transcriptomic analysis of TCGA and GEO datasets identifies a six-gene lactate metabolism signature and nominates ENO3 as a prognosis-associated ...
DNA repair kinase PRKDC helps liver cancer hide from macrophage attack
A new study reveals that PRKDC, a gene known for DNA repair, drives immune evasion in hepatocellular carcinoma by pushing ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!