Tag: tumor microenvironment

A collagen-targeted protein MRI contrast agent developed at Georgia State University detected invasive lung tumors and multi-organ metastases as small ...

A computational and laboratory study found that reducing HLTF diminished prostate cancer cell proliferation and suggested regulation of ZBP1-PANoptosome assembly ...

A multi-omics study linked ELF1 to B-cell states and breast-cancer prognosis, with cohort associations and laboratory experiments supporting further biological ...

A combined bulk and single-cell transcriptomic study identifies FLT3 and AIM2 among immune-associated genes in prostate cancer, while cell-line knockdown ...

A new review details how the immune checkpoint ligand PD-L1 doubles as a tumor-intrinsic driver of invasion through a reciprocal ...

Pancreatic ductal adenocarcinoma remains one of medicine's most unforgiving diagnoses. Despite decades of progress in surgical technique and chemotherapy, the ...

A 2026 Review argues that osteosarcoma survival and lung spread depend on stage-specific rewiring of extracellular-matrix signaling rather than one ...

An AI-driven single-cell and spatial multi-omics study defines three glioma ecosystem states and shows that a hypoxic myeloid-mesenchymal state independently ...

KIT-led researchers show that inactivating the CD44 molecule reprograms tumor-promoting fibroblasts in pancreatic cancer, reducing fibrosis and immunosuppression and shrinking ...

A multi-cohort re-analysis of melanoma transcriptomes and single-cell immune data links coordinated checkpoint-gene expression to longer overall survival, treatment-related immune ...