TREX1 enzyme shields tumors by destroying immune-activating DNA fragments
New research shows that the TREX1 exonuclease suppresses anti-tumor immunity in mice by degrading short, MRE11-derived cytosolic DNA fragments that ...
Tag: tumor immunogenicity
New Cancer Framework Ties Epigenetics, DNA Repair and Immunity Into One Immunogenicity Score
A new multi-omics framework proposes that tumor immunogenicity emerges only when epigenetic permissiveness, DNA damage response configuration and immune activation ...
Genome’s Silent Guardian: HUSH Complex Emerges as Key Player in Cancer
A systematic review in Medical Oncology details how the HUSH complex silences retrotransposons through H3K9me3 deposition and how its dysregulation ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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