PPARα Activation Overcomes Fibroinflammatory Anti-PD-1 Resistance in Liver Cancer via GSDME Pyroptosis
Hepatocellular carcinoma, the most common primary cancer of the liver, has become a major testing ground for immunotherapy. Drugs that ...
Tag: Tumor immune evasion mechanisms
Palmitate Drives Liver Metastasis by Suppressing Neutrophils’ Antitumour Activity
Liver metastases are among the most difficult complications of advanced cancer. Unlike many other organs, the liver is continuously exposed ...
NF-κB-Active Tumors, Matrix CAFs, and Immunosuppression Drive Chemoradiation Resistance in Rectal Cancer
Rectal cancer can survive one of its most aggressive treatment combinations by turning the tissue around the tumor into a ...
Donor cord blood composition may influence CAR NK cell therapy outcomes
CAR NK cell therapy is a novel immunotherapy made from natural killer (NK) cells engineered to better recognize and eliminate cancer cells At UT MD ...
Proteomic Analysis Identifies Prognostic Subgroups in SMARCA-Deficient Esophageal Cancer
A groundbreaking study has unveiled a novel proteomic landscape underlying SMARCA-deficient esophageal adenocarcinoma (EAC), shedding light on new mechanisms of ...
Common Asthma Medication Exhibits Potential in Combating Aggressive Cancers
A groundbreaking discovery from Northwestern Medicine may redefine the therapeutic landscape for aggressive cancers, revealing that a well-established asthma medication ...
New Study Reveals How Chemotherapy Modulates the Immune System to Impact Tumor Response
Chemotherapy remains a cornerstone in the fight against cancer, offering life-saving potential for many patients worldwide. However, a perplexing phenomenon ...
Reprogramming Key Immune ‘Gatekeeper’ Cell Could Enhance Cancer Immunotherapy
In a groundbreaking study published in the renowned journal Science, researchers at St. Jude Children’s Research Hospital have unveiled a ...
Targeted Epigenetic Therapy Boosts Pancreatic Cancer Immunity
A groundbreaking study has unveiled a promising therapeutic avenue for one of the most lethal forms of cancer—pancreatic ductal adenocarcinoma ...
IDO Family: Linking Metabolism, Immunity, and Tumors
Recent advancements in the field of immunology have illuminated the intricate role of the indoleamine 2,3-dioxygenase (IDO) family within the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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