MRI Radiomics Model Predicts Survival in Colorectal Cancer With Liver Metastases
A multicenter study shows that a hybrid model combining MRI radiomics, delta features, and clinical variables predicts overall survival in ...
Tag: tumor heterogeneity
AI Reveals Why Pathologists Disagree on HER2 Scoring in Breast Cancer
A Brazilian study found that an AI model's measure of HER2 staining heterogeneity within breast cancer samples predicts where pathologists ...
Hidden Genetic Fault Lines Reshape Gastric Cancer Treatment Maps in Landmark Chinese Cohort
A 563-patient genomic study from Peking University reveals how KMT2C/D loss-of-function alterations define a hypermutated, MSI-high subgroup of gastric cancer ...
Prolactin Levels May Predict Which Acromegaly Patients Stay Sick After Surgery
Single-cell RNA sequencing of pituitary tumors reveals a prolactin-associated molecular subgroup linked to failed postoperative remission in acromegaly.
Mitochondrial Quality Genes Yield Seven-Gene Prognostic Signature for Breast Cancer
Researchers report that mitochondrial quality regulation gene activity defines two prognostically distinct breast cancer subtypes and supports a seven-gene survival ...
Radiomics Meets MR Cytometry: AI Sharply Improves Breast Tumor Diagnosis on MRI
A two-center study shows that radiomic analysis of MR cytometry parameter maps outperforms mean-value-based diffusion MRI metrics for distinguishing benign ...
MRI Radiomics Model Predicts Breast Cancer Chemotherapy Response by Reading the Tumor and Its Surroundings
A machine learning study of 351 breast cancer patients shows that MRI radiomics features from both the tumor and its ...
ATP-Sensing Receptor P2RX4 Emerges as a Molecular Window Into Triple-Negative Breast Cancer’s Immune Landscape
A multi-omics study links the ATP-gated receptor P2RX4, expressed mainly by tumor cells, to macrophage marker CD163 and hypoxia signatures ...
Genetic Barcodes Reveal What Tumor Biopsies Miss
By tagging breast cancer clones with unique genetic barcodes, researchers have quantified exactly how much tumor diversity needle biopsies and ...
Blood Test and Scans Combined Reveal Hidden Patchiness in Advanced Melanoma
A longitudinal study of advanced melanoma patients shows that circulating tumor DNA tracks tumor burden and radiologic response, but its ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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