Lab-Grown Tumor Organoids Illuminate How Cancers Evade, Tolerate, and Resist Treatment
A new review in Molecular Cancer positions patient-derived organoids as living systems for mapping how cancers tolerate, persist through, and ...
Tag: tumor heterogeneity
Scientists Decode Colorectal Tumors With Imaging and Multi-Omics Fusion
A new review in the Journal of Translational Medicine maps how radiomics, pathomics and multi-omics integration can decode the tumor ...
Chemotherapy Rewrites Ovarian Cancer Drug Sensibility Without Touching the Genome
Patient-derived ovarian cancer organoids show that brief chemotherapy exposure reshapes sensitivity to second-line drugs such as cediranib and topotecan without ...
Tumors in the Same Dog Are Molecularly Worlds Apart, Landmark Study Shows
A new transcriptomic study of 179 canine mammary tumors shows that synchronous tumors within the same dog are molecularly heterogeneous ...
Massive Single-Cell Atlas Maps Five Cancer Archetypes in Multiple Myeloma
A single-cell atlas of 341 multiple myeloma patients identifies five malignant transcriptional archetypes and an orthogonal proliferative program, enabling improved ...
New AI Framework SCIGMA Unifies Spatial Multiomics Data With Built-In Uncertainty Estimates
Researchers at Brown University have developed SCIGMA, a deep learning framework that integrates up to five spatial omics modalities across ...
Scientists Build a Gene-Based Survival Model for Lung Cancer Using a Newly Defined Cell Death Pathway
Researchers constructed a fourteen-gene triaptosis-related prognostic model for lung adenocarcinoma using transcriptomic analysis, machine learning, single-cell sequencing, and experimental validation.
New Nectin-4-Targeted PET Scan Outperforms FDG in Aggressive Breast Cancer
A new gallium-68 tracer targeting Nectin-4 detected more lesions and predicted survival better than FDG PET/CT in patients with recurrent ...
Single-Cell Multi-Omics Reveals How Cancer Clones Evolve Genotype and Phenotype Together
A Nature Reviews Cancer review explains how genotype-aware single-cell multi-omics and phylogenetic reconstruction are revealing how mutant clones in healthy ...
Early Treatment Attrition After Recurrence Following Neoadjuvant Chemo-Immunotherapy in Triple-Negative Breast Cancer
Triple-negative breast cancer is sending researchers back to a difficult question: what happens when an aggressive tumor returns after receiving ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!