Cryo-EM Reveals How the ATR Checkpoint Kinase Flips Its Molecular Switch
New cryo-EM structures of human ATR–ATRIP in multiple functional states reveal how ATP priming, TopBP1 binding and autophosphorylation activate the ...
New cryo-EM structures of human ATR–ATRIP in multiple functional states reveal how ATP priming, TopBP1 binding and autophosphorylation activate the ...
© 2025 Scienmag - Science Magazine
© 2025 Scienmag - Science Magazine