Moderate pediatric burns link reduced HLA-DR with stronger TNF response
A prospective study found that moderate pediatric burns were associated with reduced monocyte HLA-DR expression but heightened early whole-blood TNF-α ...
Tag: TNF-alpha
When Joints Take a Beating: Mechanical Stress Accelerates Ankylosing Spondylitis in Mice
New mouse experiments show that compensatory mechanical microtrauma significantly worsens joint inflammation, cytokine expression, and bone destruction in a model ...
Inflammatory NF-κB Signaling Comes Alive in the Septa of Newborns with Intestinal Atresia
A study of human septal tissue from infants with type I intestinal atresia reveals markedly increased expression of NF-κB pathway ...
When the Wind Shifts, So Does the Immune System: Air Masses Leave Opposite Cytokine Fingerprints in Schizophrenia and Health
Could the weather itself leave a measurable fingerprint on the immune system of people living with schizophrenia? A new exploratory ...
Brain Inflammation and Network Changes Linked to Depression After Herpes Simplex Encephalitis
Herpes simplex encephalitis is one of the most feared infections of the human brain. Prompt antiviral therapy has dramatically improved ...
How a Single Transcription Factor Decides Whether Sunburned Skin Cells Live or Die
New research shows that the transcription factor C/EBPβ normally restrains an inflammatory interferon and TNF-α program that, when unleashed in ...
Surgery Plus Vitamin B12 Outperforms Either Alone in Peripheral Nerve Injury Trial
A randomized trial found that combining surgical neurolysis with oral methylcobalamin produced significantly better functional, electrophysiological, and anti-inflammatory outcomes in ...
Immune Cells Remodel Skin Architecture in Post-Kala-Azar Dermal Leishmaniasis
New research reveals how chemokine-driven immune infiltration and inflammatory enzymes dismantle the skin's structural framework in Post-Kala-Azar Dermal Leishmaniasis, explaining ...
Cytokine-Driven microRNA Shifts in Brain Endothelial Cells Offer New Route to Protect the Blood-Brain Barrier
A new review shows how TNF-α and IFN-γ rewire microRNA profiles in brain endothelial cells, dismantling blood-brain barrier junctions and ...
When Hepatitis C Meets Diabetes: Insulin Resistance Soars in Congolese Patients
A new Congolese study finds that patients with both chronic hepatitis C and type 2 diabetes show far worse insulin ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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