Review assesses CCT6A as a disease biomarker and therapeutic target
A 2026 review presents CCT6A as a candidate diagnostic and prognostic biomarker in cancer while highlighting context-dependent mechanisms, absent subunit-specific ...
Tag: therapeutic target
Connexin 43 Drives Liver Metastasis in Small Intestinal GIST Cells
A newly developed liver metastasis mouse model shows that the gap junction protein Connexin 43, highly expressed in small intestinal ...
Tiny Protein G0S2 Emerges as a Master Switch for Cell Death in Liver Cancer
A new proteomic study reports that the small protein G0S2 promotes apoptosis through the BAX/Caspase3 pathway, positioning it as a ...
Hidden RNA Molecule Drives Ovarian Cancer Growth by Activating Key Stress Pathway
Researchers found that the long non-coding RNA ATP6V1B1-AS1 promotes ovarian cancer growth and metastasis by binding MAP3K3 and activating the ...
Cellular Stress Hubs Help Oral Cancer Spread, Study Finds
New research shows that stress-induced eIF2α phosphorylation drives stress granule formation that promotes growth and metastasis in oral squamous cell ...
ZBED6 Loss Fuels Pathological Heart Enlargement Through a Newly Mapped Gene Switch
New research in PLOS Genetics identifies the ZBED6–MEOX1–ERK1/2 axis as a key regulator of pathological cardiac hypertrophy through impaired autophagy.
RNA-Binding RBM Proteins Emerge as Double-Edged Players in Cancer
A new review in Medical Oncology details how the RBM family of RNA-binding proteins acts as both tumor suppressors and ...
Hidden DNA Rings and a Rogue Gene Reveal Ovarian Cancer’s Adaptive Defense
A new study links HDAC inhibitor treatment to remodeling of extrachromosomal circular DNA in ovarian cancer and identifies LMO2 as ...
CD39 Emerges as a Deadly Biomarker and Drug Target in Bile Duct Cancer
New research shows that the immune enzyme CD39 is overexpressed in cholangiocarcinoma, drives tumor growth and metastasis through the ANXA2 ...
Blocking a Calcium Sensor Could Weaken Liver Cancer Cells
New research shows that inhibiting the calcium-sensing receptor with the drug NPS-2143 suppresses the proliferation, migration and invasion of liver ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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