Hidden Protein From Circular RNA Shields Colon Cancer Cells From Fiery Death
A circular RNA derived from the PIAS1 gene encodes a previously unknown 108-amino-acid protein that colon cancer cells use to ...
Tag: therapeutic target
Scientists uncover a hidden protein driver of sepsis-related organ failure
New research shows that the protein IGFBP7 drives sepsis-induced multiple organ failure by binding the mitochondrial enzyme OGDH, boosting its ...
Cellular Scissors: How the Deubiquitinase STAMBPL1 Shapes Health and Fuels Cancer
A new review details how the JAMM-family deubiquitinase STAMBPL1 maintains cellular homeostasis and, when overexpressed, drives tumor progression, metastasis, and ...
Tiny RNA Cluster Revealed as Master Switch Behind Lung Cancer Survival and Immune Evasion
Researchers at the University of Bern show that the miR105/767 microRNA cluster coordinates apoptosis, cell-cycle progression, and PD-L1 expression in ...
Neurexophilin 4 Emerges as a Molecular Driver of Kidney Cancer Through PI3K/AKT-Controlled Glycolysis
New research reveals that the protein neurexophilin 4 drives the growth, invasion and metabolic reprogramming of clear cell renal cell ...
RUNX3 Emerges as a Master Switch Behind Cancer Chemoresistance
A new review in Cancer Cell International details how the tumor suppressor RUNX3 regulates apoptosis, drug efflux, cell cycle control, ...
Astrocyte Fibronectin Emerges as Key Driver of Blood–Brain Barrier Failure in Alzheimer’s Disease
A new Nature Aging study identifies astrocyte-derived fibronectin as the molecular link between the APOE ε4 allele, amyloid pathology, and ...
Alzheimer’s disease quietly rewires the bone marrow, study finds
New research in Nature Neuroscience shows that Alzheimer's disease disrupts myeloid cell production in the bone marrow via type I ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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