Nanocarriers Aim Drugs at Pathogens Hiding Inside Cells
A new review details how lipid- and polymer-based nanocarriers can be engineered by size, shape, charge, and surface ligands to ...
Tag: Targeted therapy
Dual-Drug Liposomes With YIGSR Peptide Target Breast Tumor Cells in Mice
A YIGSR-modified liposome co-loaded with doxorubicin and 5F showed stronger cytotoxicity, higher cellular uptake and greater tumor accumulation than non-targeted ...
FLT3 inhibitors reshape acute myeloid leukemia care as trials push beyond current standards
A new review maps how FLT3 inhibitors became standard therapy across newly diagnosed and relapsed AML while trials test triplets, ...
RAS Inhibitor Daraxonrasib Redefines Pancreatic Cancer Treatment After FDA Approval
A phase 3 trial of the pan-RAS inhibitor daraxonrasib doubled median overall survival in previously treated metastatic pancreatic cancer, prompting ...
Cancer’s rogue DNA: how ecDNA reshapes itself to survive treatment
A new review in Cellular Oncology argues that treatment resistance in cancer often stems from selection and remodeling of pre-existing ...
Next-generation KRAS inhibitor divarasib extends survival in advanced lung cancer
A Phase 3 trial found the next-generation KRAS G12C inhibitor divarasib extended median overall survival to 17.7 months versus 12 ...
Review maps key signaling pathways driving oral squamous cell carcinoma and targeted therapies
A new open-access review in Discover Oncology surveys the key signaling pathways in oral squamous cell carcinoma and the targeted ...
SLC7A5 emerges as a central player in cancer amino acid metabolism
A new review summarizes how the amino acid transporter SLC7A5 drives tumor metabolic reprogramming and where targeted therapies against it ...
Engineered exosome nanocarriers emerge as targeted cardiovascular drug delivery platform
A new review outlines how engineered exosome nanocarriers could deliver drugs precisely to diseased heart tissue, while major manufacturing and ...
Polyamine-Blocking Drug DFMO Weakens Mutant K-RAS Signaling in Pancreatic Cancer Cells
A new study reports that the polyamine synthesis inhibitor DFMO suppressed mutant K-RAS downstream signaling, cell migration and invasion in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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