Chronic Inflammation Emerges as a Central Driver of Ovarian Cancer Progression
A new review in the Journal of Ovarian Research details how chronic inflammatory signaling pathways drive ovarian cancer progression and ...
Tag: Targeted therapy
Oral Wnt-blocking pill plus lenvatinib shows promise in endometrial cancer after immunotherapy fails
A phase 1b/2 trial found that the oral CBP–β-catenin inhibitor E7386 combined with lenvatinib produced durable responses in advanced endometrial ...
Two Proteins Found on Nearly All Liver Cancer Cells Point to a Dual-Target CAR-T Strategy
A study of 140 liver tumor samples shows that Glypican-3 and AXL are co-expressed in nearly all hepatocellular carcinomas, supporting ...
Chemical Tags on RNA Take Center Stage in Cancer’s Growth and Immune Evasion
A new review in Molecular Cancer details how the abundant RNA mark m6A drives cancer growth, immune evasion and treatment ...
Rare ALK Fusion Lung Cancer Shows Durable Response to First-Line Lorlatinib
A newly reported case shows that first-line lorlatinib achieved durable systemic and intracranial disease control in a patient with the ...
ADAM8/17 Emerges as a Promising Drug Target in Intrahepatic Cholangiocarcinoma
A new study identifies the enzymes ADAM8 and ADAM17 as causally linked drivers of intrahepatic cholangiocarcinoma and demonstrates that a ...
Immune checkpoint VSIR fuels gastric cancer growth by amplifying AXL signaling
New research in iScience reveals that the immune checkpoint molecule VSIR drives gastric cancer progression by transcriptionally activating and post-translationally ...
Lung Cancer Study Retracted Over Animal Ethics Concerns
A lung cancer study on buparlisib and eukaryotic elongation factor-2 has been retracted after tumors in the animal experiments exceeded ...
Fructose Fuels Pancreatic Cancer: New Vulnerability Found in KRAS G12D Tumors
A new review highlights fructose metabolism as a druggable weakness in KRAS G12D pancreatic tumors and proposes sodium citrate as ...
Lab-Grown Tumor Organoids Illuminate How Cancers Evade, Tolerate, and Resist Treatment
A new review in Molecular Cancer positions patient-derived organoids as living systems for mapping how cancers tolerate, persist through, and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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