Drug Interactions and Side Effects Shape Safe Prescribing of Lung Cancer Pills
A comprehensive review maps how food, acid-reducing drugs and liver enzymes alter the exposure of thirty lung cancer targeted therapies, ...
Tag: Targeted therapy
Liposomal Paclitaxel With HER-2 Blockers Shows Strong Real-World Results in Advanced Breast Cancer
A real-world study of 526 patients found that paclitaxel liposome combined with anti-HER-2 targeted therapies delivered median overall survival of ...
Liquid Droplets Inside Cancer Cells Explain Why a Leukemia Drug Works So Slowly
A new Cell Research study shows that BCR-ABL1 forms liquid-like phase-separated condensates inside leukemic cells that physically slow tyrosine kinase ...
Four Asia-Pacific Nations, Four Paths: Why Cancer Genomics Success Hinges on Health Systems, Not Sequencers
A landmark comparative review finds that Japan, South Korea, China, and Australia have all mastered the technology of cancer genomics, ...
Pan-RAS Inhibitor Daraxonrasib Delivers Landmark Survival Gains in Pancreatic Cancer
Two landmark New England Journal of Medicine studies show the pan-RAS inhibitor daraxonrasib nearly doubles survival in previously treated metastatic ...
Copper and Iron Cell Death Pathways Offer a New Two-Front Attack on Liver Cancer
A new review in Medical Oncology argues that simultaneously targeting copper-triggered cuproptosis and iron-dependent ferroptosis could open a powerful two-front ...
Plant Nanoparticles Deliver a Protein-Degrading Drug That Strikes Colorectal Cancer
Scientists have engineered a PROTAC molecule that destroys the RARα protein and delivered it via Polygonatum sibiricum exosome-like nanoparticles, markedly ...
Scientists Block a Survival Switch That Lets Melanoma Cells Spread
Australian researchers have shown that blocking the BRN2 transcription factor reverses anoikis resistance in melanoma cells and sensitizes them to ...
Endothelial Exosomes Emerge as Precision Tools for Cardiometabolic Disease
A new review in the Journal of Translational Medicine outlines how endothelial-derived exosomes and their molecular cargos could serve as ...
Self-Assembling Carriers Could Redefine How Drugs Reach Their Targets
A new review in the Journal of Advanced Research details how self-assembling delivery platforms built from peptides, polyelectrolytes and natural ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!