Tag: Targeted therapy

Researchers found that tracking CDK1 protein activity could help identify which estrogen receptor-positive breast cancers become resistant to CDK4/6 inhibitor ...

A scientific review details the bidirectional regulatory network between breast cancer cells and their surrounding microenvironment that drives therapy resistance.

A perspective in Discover Oncology highlights integrative frameworks to decode how cellular adaptations and microenvironment interactions drive drug resistance in ...

Researchers have proposed a self-reinforcing RUNX2 and TGF-beta feedback loop as a working hypothesis to explain chemoresistance in triple-negative breast ...

A systematic review evaluates the role of the actin-binding protein ACTN4 in tumorigenesis and the challenges of targeting it in ...

Elevated FOLR1 expression promotes sorafenib resistance in hepatocellular carcinoma cells by enhancing folic acid uptake and reactivating the SRC and ...

Researchers have found that the breast cancer drug abemaciclib suppresses tumor growth and halts signaling in preclinical lung cancer models ...

A new clinical guide in Frontiers in Oncology outlines an integrated care pathway for young-onset lung cancer, emphasizing urgent genomic ...

A retrospective case report details the diagnosis and multimodal treatment of a 39-year-old female patient with primary pulmonary artery sarcoma ...

A systematic review indicates that combining novel molecular markers with pathway-targeted therapies improves diagnosis, prognostic stratification, and individualized treatment in ...