Lung Cancer That Hid in the Uterus: Rare Metastasis Fooled Doctors
A 77-year-old woman's uterine tumor turned out to be metastatic lung adenocarcinoma, a case highlighting how immunohistochemistry and genomic sequencing ...
Tag: Targeted therapy
Three-Day Whole Genome Sequencing Transforms Childhood Cancer Diagnosis
A UK study shows rapid whole genome sequencing cuts pediatric cancer diagnosis time from six weeks to three days while ...
Ovarian Cancer Cells Outsmart CXCR4 Blockade at High Doses, Study Finds
New research shows that blocking the CXCL12/CXCR4 signaling axis in ovarian cancer cells produces a paradoxical biphasic response, with moderate ...
A Rare EBV-Negative NK/T-Cell Lymphoma in an Infant Challenges What Doctors Know
A fulminant, disseminated, EBV-negative extranodal NK/T-cell lymphoma in a previously healthy infant was diagnosed only after death, underscoring the rarity ...
AI Reads Tumor Slides to Predict Melanoma Gene Mutations, Offering Faster Targeted Therapy Triage
A new study shows that AI models trained on routine pathology slides can predict BRAF mutation status in melanoma patients ...
New Myasthenia Gravis Playbook Pairs Fast-Acting Antibody Blockers With Long-Term Immune Therapies
Seven real-world cases from a Greek neuromuscular center show how FcRn antagonists, rituximab and ravulizumab can be sequenced in generalized ...
TRK Protein Staining in Childhood Rhabdomyosarcoma Flags Aggressive Tumors but Misses the Gene Fusions That Matter
A Hungarian study of 45 pediatric rhabdomyosarcoma cases found TRK protein expression in 38 percent of tumors—concentrated in the aggressive ...
Thirteen Years of Infection Data Reveal a Safer Path for Leukemia Induction Therapy
A 13-year Polish study of 219 acute myeloid leukemia patients shows that stopping fluoroquinolone prophylaxis in 2018 was clinically safe, ...
Itch Relief Arrives Before Skin Healing in Prurigo Nodularis, Landmark Analysis of 11 Trials Finds
A new meta-analysis of 11 randomized trials shows dupilumab and nemolizumab deliver robust itch and lesion relief in prurigo nodularis, ...
Copper Nanoparticles Emerge as Multifunctional Weapons in Drug Delivery and Cancer Therapy
A comprehensive review highlights how copper nanoparticles combine drug delivery, targeted tumor therapy, and the newly discovered cell death pathway ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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