313TE targets IL-13Rα2-positive tumors in preclinical testing
A preclinical study reports that the IL-13E13Y-based T-cell engager 313TE linked IL-13Rα2-positive tumor cells to T cells, promoting receptor-dependent killing ...
Tag: T-cell engager
AI-Designed Protein Drug Recruits Immune Cells to Fight Gastric Cancer—With a Helping Hand from Dendritic Cells
A team at Nanjing Medical University used RFdiffusion to design a CLDN18.2-targeting T-cell engager for gastric cancer and showed that ...
T Cell-Engaging Antibody Clears Aging Cells in Mice and Monkeys, With Liver Enzymes as a Built-In Safety Gauge
A uPAR-targeting bispecific T-cell engager safely cleared senescent cells in aged mice and rhesus macaques, with serum liver enzymes serving ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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